STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PIP4P2Phosphatidylinositol-4,5-bisphosphate 4-phosphatase; Catalyzes the hydrolysis of phosphatidylinositol-4,5- bisphosphate (PtdIns-4,5-P2) to phosphatidylinositol-4-phosphate (PtdIns-4-P). (257 aa)    
Predicted Functional Partners:
MTMR4
Myotubularin related protein 4.
 
 
 
 0.946
PIP4K2A
Phosphatidylinositol-5-phosphate 4-kinase type 2 alpha.
     
 0.923
PIP4K2B
Phosphatidylinositol-5-phosphate 4-kinase type 2 beta.
   
 
 0.919
PIP4K2C
Phosphatidylinositol-5-phosphate 4-kinase type 2 gamma.
     
 0.918
MTMR3
Myotubularin related protein 3.
 
   
 0.913
PIP5K1A
PIPK domain-containing protein.
     
 0.910
PIP5K1B
Phosphatidylinositol-4-phosphate 5-kinase type 1 beta.
     
 0.910
PIP5K1C
Phosphatidylinositol-4-phosphate 5-kinase type 1 gamma.
     
 0.910
INPP5E
Inositol polyphosphate-5-phosphatase E.
   
 
 0.906
PIKFYVE
Phosphoinositide kinase, FYVE-type zinc finger containing.
     
 0.904
Your Current Organism:
Equus caballus
NCBI taxonomy Id: 9796
Other names: E. caballus, Equus przewalskii f. caballus, Equus przewalskii forma caballus, domestic horse, equine, horse
Server load: low (24%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.