STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SFXN4Sideroflexin 4. (390 aa)    
Predicted Functional Partners:
MTFR1
Mitochondrial fission regulator 1.
      
 0.735
XPNPEP2
X-prolyl aminopeptidase 2; Belongs to the peptidase M24B family.
   
  
 0.701
DNAJC19
DnaJ heat shock protein family (Hsp40) member C19.
   
  
 0.686
SLC25A36
Solute carrier family 25 member 36; Belongs to the mitochondrial carrier (TC 2.A.29) family.
   
  
 0.685
NOSIP
Nitric oxide synthase-interacting protein; Negatively regulates nitric oxide production by inducing NOS1 and NOS3 translocation to actin cytoskeleton and inhibiting their enzymatic activity; Belongs to the NOSIP family.
   
  
 0.681
FDX1
Ferredoxin 1.
   
  
 0.679
CPOX
Coproporphyrinogen oxidase.
   
 
 0.646
AGK
Acylglycerol kinase.
   
 
 0.643
TIMM22
Translocase of inner mitochondrial membrane 22.
   
  
 0.632
SFXN2
Sidoreflexin.
  
 
0.630
Your Current Organism:
Equus caballus
NCBI taxonomy Id: 9796
Other names: E. caballus, Equus przewalskii f. caballus, Equus przewalskii forma caballus, domestic horse, equine, horse
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.