STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
ALDH4A1Aldehyde dehydrogenase 4 family member A1; Belongs to the aldehyde dehydrogenase family. (498 aa)    
Predicted Functional Partners:
ALDH18A1
Delta-1-pyrroline-5-carboxylate synthase; In the C-terminal section; belongs to the gamma-glutamyl phosphate reductase family.
  
 
 0.918
GCSH
Glycine cleavage system H protein; The H protein shuttles the methylamine group of glycine from the P protein to the T protein; Belongs to the GcvH family.
   
 
 0.916
OAT
Ornithine aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
  
 0.909
PRODH2
Proline dehydrogenase; Converts proline to delta-1-pyrroline-5-carboxylate.
  
 0.885
GLUD1
ELFV_dehydrog domain-containing protein; Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
  
 0.882
DLD
Dihydrolipoyl dehydrogenase.
   
 0.863
GLS2
Glutaminase 2.
  
 
 0.859
GLUL
Glutamine synthetase.
  
 
 0.858
EPRS1
Glutamyl-prolyl-tRNA synthetase.
  
 
 0.842
GOT2
Aspartate aminotransferase, mitochondrial; Catalyzes the irreversible transamination of the L-tryptophan metabolite L-kynurenine to form kynurenic acid (KA). Plays a key role in amino acid metabolism. Important for metabolite exchange between mitochondria and cytosol. Facilitates cellular uptake of long-chain free fatty acids (By similarity).
   
 0.839
Your Current Organism:
Equus caballus
NCBI taxonomy Id: 9796
Other names: E. caballus, Equus przewalskii f. caballus, Equus przewalskii forma caballus, domestic horse, equine, horse
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