Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
DTWD1DTW domain containing 1. (310 aa)    
Predicted Functional Partners:
TSR3
Probable ribosome biogenesis protein C16orf42 homolog; Probable pre-rRNA processing protein involved in ribosome biogenesis.
      
 0.955
DTWD2
DTW domain containing 2.
      
 0.955
DUS2
Dihydrouridine synthase 2.
      
 0.955
DUS4L
tRNA-dihydrouridine synthase; Catalyzes the synthesis of dihydrouridine, a modified base found in the D-loop of most tRNAs; Belongs to the dus family.
   
  
 0.822
LIPJ
Lipase; Belongs to the AB hydrolase superfamily. Lipase family.
      
 0.777
FGF7
Fibroblast growth factor; Belongs to the heparin-binding growth factors family.
 
      0.602
MPHOSPH10
U3 small nucleolar ribonucleoprotein protein MPP10; Component of the 60-80S U3 small nucleolar ribonucleoprotein (U3 snoRNP). Required for the early cleavages during pre-18S ribosomal RNA processing; Belongs to the MPP10 family.
      
 0.566
CCDC85C
Coiled-coil domain containing 85C.
      
 0.555
NIFK
Nucleolar protein interacting with the FHA domain of MKI67.
      
 0.553
NDUFAF5
NADH:ubiquinone oxidoreductase complex assembly factor 5.
      
 0.510
Your Current Organism:
Equus caballus
NCBI taxonomy Id: 9796
Other names: E. caballus, Equus przewalskii f. caballus, Equus przewalskii forma caballus, domestic horse, equine, horse
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