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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PNPLA1Patatin like phospholipase domain containing 1. (525 aa)    
Predicted Functional Partners:
LIPN
Lipase; Belongs to the AB hydrolase superfamily. Lipase family.
    
 
 0.913
NIPAL4
NIPA like domain containing 4.
   
  
 0.906
CYP4F22
Cytochrome P450 family 4 subfamily F member 22; Belongs to the cytochrome P450 family.
      
 0.886
CERS3
Ceramide synthase 3.
      
 0.850
TGM1
Transglutaminase 1.
   
  
 0.825
ABCA12
ATP binding cassette subfamily A member 12.
   
  
 0.811
SLC27A4
Solute carrier family 27 member 4.
    
 
 0.807
SDR9C7
Short chain dehydrogenase/reductase family 9C member 7; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
      
 0.797
ABHD5
Abhydrolase domain containing 5.
    
 
 0.778
SULT2B1
Sulfotransferase; Belongs to the sulfotransferase 1 family.
   
  
 0.728
Your Current Organism:
Equus caballus
NCBI taxonomy Id: 9796
Other names: E. caballus, Equus przewalskii f. caballus, Equus przewalskii forma caballus, domestic horse, equine, horse
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.