Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
NPTX2Neuronal pentraxin 2. (430 aa)    
Predicted Functional Partners:
CBX6
Chromobox 6.
 
      0.816
NPTXR
Neuronal pentraxin receptor.
   
 
 0.647
GRIA2
Glutamate ionotropic receptor AMPA type subunit 2.
   
 
 0.625
GASK1B
Golgi associated kinase 1B.
      
 0.571
SNPH
RAD21 cohesin complex component like 1.
   
  
 0.558
BICC1
BicC family RNA binding protein 1.
      
 0.551
PCSK1
Proprotein convertase subtilisin/kexin type 1; Belongs to the peptidase S8 family.
   
  
 0.550
C1QB
Complement C1q B chain.
      
 0.545
RNF2
Ring finger protein 2.
    
 0.539
RING1
Ring finger protein 1.
    
 0.539
Your Current Organism:
Equus caballus
NCBI taxonomy Id: 9796
Other names: E. caballus, Equus przewalskii f. caballus, Equus przewalskii forma caballus, domestic horse, equine, horse
Server load: low (24%) [HD]