ALOX5AP protein (Equus caballus) - STRING interaction network

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ALOX5AP

Arachidonate 5-lipoxygenase-activating protein; Required for leukotriene biosynthesis by ALOX5 (5- lipoxygenase). Anchors ALOX5 to the membrane. Binds arachidonic acid, and could play an essential role in the transfer of arachidonic acid to ALOX5. Binds to MK-886, a compound that blocks the biosynthesis of leukotrienes (By similarity); Belongs to the MAPEG family. (187 aa)

Predicted Functional Partners:

ALOX12B

0.745

LTA4H

0.739

ALOX12

0.701

LTC4S

0.586

MGST2

0.554

ALOX5

0.536

ALOX15

0.528

ITGB2

0.514

ALOX15B

0.504

MEDAG

0.493

Your Current Organism:

Equus caballus

NCBI taxonomy Id: 9796
Other names: E. caballus, Equus przewalskii f. caballus, Equus przewalskii forma caballus, domestic horse, equine, horse

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ALOX12	ALOX12B	ENSECAP00000019594	ENSECAP00000010462	Arachidonate 12-lipoxygenase, 12S type.	Arachidonate 12-lipoxygenase, 12R type.	0.906
ALOX12	ALOX15B	ENSECAP00000019594	ENSECAP00000010415	Arachidonate 12-lipoxygenase, 12S type.	Arachidonate 15-lipoxygenase type B.	0.454
ALOX12	ALOX5	ENSECAP00000019594	ENSECAP00000045479	Arachidonate 12-lipoxygenase, 12S type.	Arachidonate 5-lipoxygenase.	0.937
ALOX12	ALOX5AP	ENSECAP00000019594	ENSECAP00000033016	Arachidonate 12-lipoxygenase, 12S type.	Arachidonate 5-lipoxygenase-activating protein; Required for leukotriene biosynthesis by ALOX5 (5- lipoxygenase). Anchors ALOX5 to the membrane. Binds arachidonic acid, and could play an essential role in the transfer of arachidonic acid to ALOX5. Binds to MK-886, a compound that blocks the biosynthesis of leukotrienes (By similarity); Belongs to the MAPEG family.	0.701
ALOX12B	ALOX12	ENSECAP00000010462	ENSECAP00000019594	Arachidonate 12-lipoxygenase, 12R type.	Arachidonate 12-lipoxygenase, 12S type.	0.906
ALOX12B	ALOX5	ENSECAP00000010462	ENSECAP00000045479	Arachidonate 12-lipoxygenase, 12R type.	Arachidonate 5-lipoxygenase.	0.939
ALOX12B	ALOX5AP	ENSECAP00000010462	ENSECAP00000033016	Arachidonate 12-lipoxygenase, 12R type.	Arachidonate 5-lipoxygenase-activating protein; Required for leukotriene biosynthesis by ALOX5 (5- lipoxygenase). Anchors ALOX5 to the membrane. Binds arachidonic acid, and could play an essential role in the transfer of arachidonic acid to ALOX5. Binds to MK-886, a compound that blocks the biosynthesis of leukotrienes (By similarity); Belongs to the MAPEG family.	0.745
ALOX15	ALOX5AP	ENSECAP00000042439	ENSECAP00000033016	Arachidonate 15-lipoxygenase.	Arachidonate 5-lipoxygenase-activating protein; Required for leukotriene biosynthesis by ALOX5 (5- lipoxygenase). Anchors ALOX5 to the membrane. Binds arachidonic acid, and could play an essential role in the transfer of arachidonic acid to ALOX5. Binds to MK-886, a compound that blocks the biosynthesis of leukotrienes (By similarity); Belongs to the MAPEG family.	0.528
ALOX15B	ALOX12	ENSECAP00000010415	ENSECAP00000019594	Arachidonate 15-lipoxygenase type B.	Arachidonate 12-lipoxygenase, 12S type.	0.454
ALOX15B	ALOX5AP	ENSECAP00000010415	ENSECAP00000033016	Arachidonate 15-lipoxygenase type B.	Arachidonate 5-lipoxygenase-activating protein; Required for leukotriene biosynthesis by ALOX5 (5- lipoxygenase). Anchors ALOX5 to the membrane. Binds arachidonic acid, and could play an essential role in the transfer of arachidonic acid to ALOX5. Binds to MK-886, a compound that blocks the biosynthesis of leukotrienes (By similarity); Belongs to the MAPEG family.	0.504
ALOX5	ALOX12	ENSECAP00000045479	ENSECAP00000019594	Arachidonate 5-lipoxygenase.	Arachidonate 12-lipoxygenase, 12S type.	0.937
ALOX5	ALOX12B	ENSECAP00000045479	ENSECAP00000010462	Arachidonate 5-lipoxygenase.	Arachidonate 12-lipoxygenase, 12R type.	0.939
ALOX5	ALOX5AP	ENSECAP00000045479	ENSECAP00000033016	Arachidonate 5-lipoxygenase.	Arachidonate 5-lipoxygenase-activating protein; Required for leukotriene biosynthesis by ALOX5 (5- lipoxygenase). Anchors ALOX5 to the membrane. Binds arachidonic acid, and could play an essential role in the transfer of arachidonic acid to ALOX5. Binds to MK-886, a compound that blocks the biosynthesis of leukotrienes (By similarity); Belongs to the MAPEG family.	0.536
ALOX5	LTA4H	ENSECAP00000045479	ENSECAP00000007418	Arachidonate 5-lipoxygenase.	Leukotriene A(4) hydrolase; Belongs to the peptidase M1 family.	0.919
ALOX5	LTC4S	ENSECAP00000045479	ENSECAP00000018123	Arachidonate 5-lipoxygenase.	Leukotriene C4 synthase.	0.931
ALOX5AP	ALOX12	ENSECAP00000033016	ENSECAP00000019594	Arachidonate 5-lipoxygenase-activating protein; Required for leukotriene biosynthesis by ALOX5 (5- lipoxygenase). Anchors ALOX5 to the membrane. Binds arachidonic acid, and could play an essential role in the transfer of arachidonic acid to ALOX5. Binds to MK-886, a compound that blocks the biosynthesis of leukotrienes (By similarity); Belongs to the MAPEG family.	Arachidonate 12-lipoxygenase, 12S type.	0.701
ALOX5AP	ALOX12B	ENSECAP00000033016	ENSECAP00000010462	Arachidonate 5-lipoxygenase-activating protein; Required for leukotriene biosynthesis by ALOX5 (5- lipoxygenase). Anchors ALOX5 to the membrane. Binds arachidonic acid, and could play an essential role in the transfer of arachidonic acid to ALOX5. Binds to MK-886, a compound that blocks the biosynthesis of leukotrienes (By similarity); Belongs to the MAPEG family.	Arachidonate 12-lipoxygenase, 12R type.	0.745
ALOX5AP	ALOX15	ENSECAP00000033016	ENSECAP00000042439	Arachidonate 5-lipoxygenase-activating protein; Required for leukotriene biosynthesis by ALOX5 (5- lipoxygenase). Anchors ALOX5 to the membrane. Binds arachidonic acid, and could play an essential role in the transfer of arachidonic acid to ALOX5. Binds to MK-886, a compound that blocks the biosynthesis of leukotrienes (By similarity); Belongs to the MAPEG family.	Arachidonate 15-lipoxygenase.	0.528
ALOX5AP	ALOX15B	ENSECAP00000033016	ENSECAP00000010415	Arachidonate 5-lipoxygenase-activating protein; Required for leukotriene biosynthesis by ALOX5 (5- lipoxygenase). Anchors ALOX5 to the membrane. Binds arachidonic acid, and could play an essential role in the transfer of arachidonic acid to ALOX5. Binds to MK-886, a compound that blocks the biosynthesis of leukotrienes (By similarity); Belongs to the MAPEG family.	Arachidonate 15-lipoxygenase type B.	0.504
ALOX5AP	ALOX5	ENSECAP00000033016	ENSECAP00000045479	Arachidonate 5-lipoxygenase-activating protein; Required for leukotriene biosynthesis by ALOX5 (5- lipoxygenase). Anchors ALOX5 to the membrane. Binds arachidonic acid, and could play an essential role in the transfer of arachidonic acid to ALOX5. Binds to MK-886, a compound that blocks the biosynthesis of leukotrienes (By similarity); Belongs to the MAPEG family.	Arachidonate 5-lipoxygenase.	0.536

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