Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
COX7A2Cytochrome c oxidase subunit 7A2. (90 aa)    
Predicted Functional Partners:
COX5B
Cytochrome c oxidase subunit 5B.
   
 0.999
COX6A1
Cytochrome c oxidase subunit 6A, mitochondrial.
   
 0.999
LOC100630549
Uncharacterized protein.
   
 0.999
COX7B
Cytochrome c oxidase subunit 7B.
   
 0.998
COX4I1
Cytochrome c oxidase subunit 4I1.
   
 0.997
COX5A
Cytochrome c oxidase subunit 5A.
   
 0.996
COX2
Cytochrome c oxidase subunit 2; Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol- cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and t [...]
   
 0.994
COX8A
Cytochrome c oxidase subunit 8A.
   
 0.993
UQCRB
Ubiquinol-cytochrome c reductase binding protein.
   
 0.992
COX4I2
Cytochrome c oxidase subunit 4I2.
   
 0.991
Your Current Organism:
Equus caballus
NCBI taxonomy Id: 9796
Other names: E. caballus, Equus przewalskii f. caballus, Equus przewalskii forma caballus, domestic horse, equine, horse
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