STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
COMTD1Catechol-O-methyltransferase domain containing 1. (262 aa)    
Predicted Functional Partners:
TK1
Thymidine kinase.
  
 
  0.814
TYMP
Thymidine phosphorylase; Catalyzes the reversible phosphorolysis of thymidine. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis. Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family.
    
  0.775
DUS2
Dihydrouridine synthase 2.
  
  
 0.768
COPRS
Coordinator of PRMT5 and differentiation stimulator.
   
  
 0.727
PAXBP1
PAX3 and PAX7 binding protein 1.
   
  
 0.725
TMC4
Transmembrane channel-like protein.
   
  
 0.715
MAP6D1
MAP6 domain containing 1.
    
 
 0.706
SSC5D
Scavenger receptor cysteine rich family member with 5 domains.
   
  
 0.681
TBC1D14
TBC1 domain family member 14.
      
 0.671
MAT2A
S-adenosylmethionine synthase; Catalyzes the formation of S-adenosylmethionine from methionine and ATP.
  
 
 0.645
Your Current Organism:
Equus caballus
NCBI taxonomy Id: 9796
Other names: E. caballus, Equus przewalskii f. caballus, Equus przewalskii forma caballus, domestic horse, equine, horse
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