Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
KCNMA1Potassium calcium-activated channel subfamily M alpha 1. (1278 aa)    
Predicted Functional Partners:
KCNMB1
Potassium calcium-activated channel subfamily M regulatory beta subunit 1.
    
 0.978
KCNN4
Potassium calcium-activated channel subfamily N member 4.
   
 
 0.970
KCNN3
Potassium calcium-activated channel subfamily N member 3.
   
 
 0.943
PRKACA
Protein kinase cAMP-activated catalytic subunit alpha; Belongs to the protein kinase superfamily.
    
 0.933
PRKACB
Protein kinase cAMP-activated catalytic subunit beta; Belongs to the protein kinase superfamily.
    
 0.933
CACNA1S
Voltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family.
   
 0.926
KCNMB4
Potassium calcium-activated channel subfamily M regulatory beta subunit 4.
     
 0.920
KCNMB3
Potassium calcium-activated channel subfamily M regulatory beta subunit 3.
     
 0.919
PRKG1
cGMP-dependent protein kinase.
   
 
 0.918
KCNMB2
Potassium calcium-activated channel subfamily M regulatory beta subunit 2.
    
 0.915
Your Current Organism:
Equus caballus
NCBI taxonomy Id: 9796
Other names: E. caballus, Equus przewalskii f. caballus, Equus przewalskii forma caballus, domestic horse, equine, horse
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