Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
AKIRIN1Uncharacterized protein. (193 aa)    
Predicted Functional Partners:
AKIRIN2
Akirin 2.
   
   0.809
PSMA5
Proteasome subunit alpha type.
   
   0.541
MEF2B
Myocyte enhancer factor 2B.
      
 0.511
MSTN
Growth/differentiation factor 8; Acts specifically as a negative regulator of skeletal muscle growth; Belongs to the TGF-beta family.
      
 0.510
PSMA2
Proteasome subunit alpha type.
   
   0.499
SMARCD2
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 2.
    
 
 0.448
SMARCD1
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 1.
    
 
 0.448
SMARCD3
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3.
    
 
 0.448
PSMB9
Proteasome subunit beta 9.
    
   0.428
Your Current Organism:
Equus caballus
NCBI taxonomy Id: 9796
Other names: E. caballus, Equus przewalskii f. caballus, Equus przewalskii forma caballus, domestic horse, equine, horse
Server load: low (12%) [HD]