STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TREML1Triggering receptor expressed on myeloid cells like 1. (289 aa)    
Predicted Functional Partners:
FGL1
Fibrinogen like 1.
      
 0.859
TREM2
Triggering receptor expressed on myeloid cells 2.
 
   
 0.808
TREM1
Triggering receptor expressed on myeloid cells 1.
   
 
 0.757
GRN
Antimicrobial peptide eNAP-1; Has antimicrobial activity against Gram-negative and Gram- positive bacteria; Belongs to the granulin family.
   
  
 0.692
TREML2
Triggering receptor expressed on myeloid cells like 2.
 
 
 
0.640
FN1
Fibronectin; Fibronectins bind cell surfaces and various compounds including collagen, fibrin, heparin, DNA, and actin. Fibronectins are involved in cell adhesion, cell motility, opsonization, wound healing, and maintenance of cell shape. Involved in osteoblast compaction through the fibronectin fibrillogenesis cell-mediated matrix assembly process, essential for osteoblast mineralization. Participates in the regulation of type I collagen deposition by osteoblasts (By similarity).
      
 0.568
ITGA2B
Integrin subunit alpha 2b; Belongs to the integrin alpha chain family.
   
 
 0.547
GP9
Glycoprotein IX platelet.
   
  
 0.521
ACRBP
Acrosin binding protein.
   
    0.504
LHB
Lutropin/choriogonadotropin subunit beta; Promotes spermatogenesis and ovulation by stimulating the testes and ovaries to synthesize steroids; Belongs to the glycoprotein hormones subunit beta family.
      
 0.483
Your Current Organism:
Equus caballus
NCBI taxonomy Id: 9796
Other names: E. caballus, Equus przewalskii f. caballus, Equus przewalskii forma caballus, domestic horse, equine, horse
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.