Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
LOC100069576Fibronectin type-III domain-containing protein. (823 aa)    
Predicted Functional Partners:
LOC102148014
Uncharacterized protein.
   
 0.964
JAK2
Tyrosine-protein kinase.
   
 0.960
CSF2
Granulocyte-macrophage colony-stimulating factor.
    
 0.956
JAK1
Tyrosine-protein kinase.
   
 0.919
ENSECAP00000026252
Uncharacterized protein.
   
 0.912
IL5
Interleukin-5; Factor that induces terminal differentiation of late- developing B-cells to immunoglobulin secreting cells.
    
 0.904
JAK3
Tyrosine-protein kinase.
   
 0.903
IL5RA
Interleukin 5 receptor subunit alpha.
    
 0.899
ENSECAP00000030960
Uncharacterized protein.
   
 0.856
PTPN6
Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily.
   
 0.799
Your Current Organism:
Equus caballus
NCBI taxonomy Id: 9796
Other names: E. caballus, Equus przewalskii f. caballus, Equus przewalskii forma caballus, domestic horse, equine, horse
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