Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
CHDHCholine dehydrogenase. (594 aa)    
Predicted Functional Partners:
ALDH7A1
Aldehyde dehydrogenase 7 family member A1; Belongs to the aldehyde dehydrogenase family.
  
 
 0.938
PEMT
Phosphatidylethanolamine N-methyltransferase; Catalyzes the three sequential steps of the methylation pathway of phosphatidylcholine biosynthesis, the SAM-dependent methylation of phosphatidylethanolamine (PE) to phosphatidylmonomethylethanolamine (PMME), PMME to phosphatidyldimethylethanolamine (PDME), and PDME to phosphatidylcholine (PC); Belongs to the class VI-like SAM-binding methyltransferase superfamily. PEMT/PEM2 methyltransferase family.
   
 
 0.932
CEPT1
Choline/ethanolamine phosphotransferase 1; Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
     
 0.913
JMJD7
Phospholipase A2.
     
 0.904
PISD
Phosphatidylserine decarboxylase.
     
 0.901
MBOAT1
Membrane bound O-acyltransferase domain containing 1; Belongs to the membrane-bound acyltransferase family.
   
 
 0.900
PLA2G2F
Phospholipase A(2).
     
 0.898
LPCAT3
Lysophosphatidylcholine acyltransferase 3; Belongs to the membrane-bound acyltransferase family.
     
 0.898
PLAAT3
Phospholipase A and acyltransferase 3.
   
 
 0.897
PLA2G4F
Phospholipase A2.
     
 0.896
Your Current Organism:
Equus caballus
NCBI taxonomy Id: 9796
Other names: E. caballus, Equus przewalskii f. caballus, Equus przewalskii forma caballus, domestic horse, equine, horse
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