STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ARNTLAryl hydrocarbon receptor nuclear translocator-like protein 1; Transcriptional activator which forms a core component of the circadian clock. The circadian clock, an internal time-keeping system, regulates various physiological processes through the generation of approximately 24 hour circadian rhythms in gene expression, which are translated into rhythms in metabolism and behavior. It is derived from the Latin roots 'circa' (about) and 'diem' (day) and acts as an important regulator of a wide array of physiological functions including metabolism, sleep, body temperature, blood pressur [...] (626 aa)    
Predicted Functional Partners:
CRY2
Cryptochrome circadian regulator 2.
   
 0.999
CRY1
Cryptochrome circadian regulator 1.
   
 0.999
CLOCK
Clock circadian regulator.
   
0.998
NPAS2
Neuronal PAS domain protein 2.
   
0.996
PER2
Period circadian regulator 2.
    
0.983
LOC100055155
Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.
    
 0.975
CSNK1D
Casein kinase 1 delta; Belongs to the protein kinase superfamily.
    
 0.974
NPAS4
Neuronal PAS domain protein 4.
    
0.963
NR1D1
Nuclear receptor subfamily 1 group D member 1.
     
 0.888
SIRT1
Sirtuin 1.
   
 0.867
Your Current Organism:
Equus caballus
NCBI taxonomy Id: 9796
Other names: E. caballus, Equus przewalskii f. caballus, Equus przewalskii forma caballus, domestic horse, equine, horse
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