STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CCND2Cyclin D2; Belongs to the cyclin family. (289 aa)    
Predicted Functional Partners:
CDK4
Cyclin dependent kinase 4; Belongs to the protein kinase superfamily.
   
 0.999
CDK6
Cyclin dependent kinase 6; Belongs to the protein kinase superfamily.
   
 0.999
CDKN1B
Cyclin dependent kinase inhibitor 1B.
   
 0.986
CDKN1A
Cyclin dependent kinase inhibitor 1A.
   
 0.985
RB1
RB transcriptional corepressor 1.
    
 0.976
CDKN2C
Cyclin dependent kinase inhibitor 2C.
   
 0.974
CDKN1C
Cyclin dependent kinase inhibitor 1C.
   
 0.974
RBL2
RB transcriptional corepressor like 2.
    
 0.973
RBL1
RB transcriptional corepressor like 1.
   
 0.973
CDKN2A
Cyclin dependent kinase inhibitor 2A.
    
 0.965
Your Current Organism:
Equus caballus
NCBI taxonomy Id: 9796
Other names: E. caballus, Equus przewalskii f. caballus, Equus przewalskii forma caballus, domestic horse, equine, horse
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.