MIF protein (Equus caballus) - STRING interaction network

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Score

MIF

Macrophage migration inhibitory factor. (115 aa)

Predicted Functional Partners:

CD74

0.990

GOT1

0.917

TAT

0.916

GOT2

0.913

HPD

0.911

GOT1L1

0.910

LOC100147151

0.902

LOC100055246

0.902

IL4I1

0.901

CXCR4

0.716

Your Current Organism:

Equus caballus

NCBI taxonomy Id: 9796
Other names: E. caballus, Equus przewalskii f. caballus, Equus przewalskii forma caballus, domestic horse, equine, horse

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CD74	CXCR4	ENSECAP00000039301	ENSECAP00000002602	CD74 molecule.	C-X-C motif chemokine receptor 4; Belongs to the G-protein coupled receptor 1 family.	0.816
CD74	MIF	ENSECAP00000039301	ENSECAP00000010567	CD74 molecule.	Macrophage migration inhibitory factor.	0.990
CXCR4	CD74	ENSECAP00000002602	ENSECAP00000039301	C-X-C motif chemokine receptor 4; Belongs to the G-protein coupled receptor 1 family.	CD74 molecule.	0.816
CXCR4	MIF	ENSECAP00000002602	ENSECAP00000010567	C-X-C motif chemokine receptor 4; Belongs to the G-protein coupled receptor 1 family.	Macrophage migration inhibitory factor.	0.716
GOT1	GOT1L1	ENSECAP00000000135	ENSECAP00000013482	Aspartate aminotransferase, cytoplasmic; Biosynthesis of L-glutamate from L-aspartate or L-cysteine. Important regulator of levels of glutamate, the major excitatory neurotransmitter of the vertebrate central nervous system. Acts as a scavenger of glutamate in brain neuroprotection. The aspartate aminotransferase activity is involved in hepatic glucose synthesis during development and in adipocyte glyceroneogenesis. Using L-cysteine as substrate, regulates levels of mercaptopyruvate, an important source of hydrogen sulfide. Mercaptopyruvate is converted into H(2)S via the action of 3-m [...]	Glutamic-oxaloacetic transaminase 1 like 1.	0.913
GOT1	GOT2	ENSECAP00000000135	ENSECAP00000014550	Aspartate aminotransferase, cytoplasmic; Biosynthesis of L-glutamate from L-aspartate or L-cysteine. Important regulator of levels of glutamate, the major excitatory neurotransmitter of the vertebrate central nervous system. Acts as a scavenger of glutamate in brain neuroprotection. The aspartate aminotransferase activity is involved in hepatic glucose synthesis during development and in adipocyte glyceroneogenesis. Using L-cysteine as substrate, regulates levels of mercaptopyruvate, an important source of hydrogen sulfide. Mercaptopyruvate is converted into H(2)S via the action of 3-m [...]	Aspartate aminotransferase, mitochondrial; Catalyzes the irreversible transamination of the L-tryptophan metabolite L-kynurenine to form kynurenic acid (KA). Plays a key role in amino acid metabolism. Important for metabolite exchange between mitochondria and cytosol. Facilitates cellular uptake of long-chain free fatty acids (By similarity).	0.982
GOT1	HPD	ENSECAP00000000135	ENSECAP00000009738	Aspartate aminotransferase, cytoplasmic; Biosynthesis of L-glutamate from L-aspartate or L-cysteine. Important regulator of levels of glutamate, the major excitatory neurotransmitter of the vertebrate central nervous system. Acts as a scavenger of glutamate in brain neuroprotection. The aspartate aminotransferase activity is involved in hepatic glucose synthesis during development and in adipocyte glyceroneogenesis. Using L-cysteine as substrate, regulates levels of mercaptopyruvate, an important source of hydrogen sulfide. Mercaptopyruvate is converted into H(2)S via the action of 3-m [...]	4-hydroxyphenylpyruvate dioxygenase.	0.957
GOT1	IL4I1	ENSECAP00000000135	ENSECAP00000015625	Aspartate aminotransferase, cytoplasmic; Biosynthesis of L-glutamate from L-aspartate or L-cysteine. Important regulator of levels of glutamate, the major excitatory neurotransmitter of the vertebrate central nervous system. Acts as a scavenger of glutamate in brain neuroprotection. The aspartate aminotransferase activity is involved in hepatic glucose synthesis during development and in adipocyte glyceroneogenesis. Using L-cysteine as substrate, regulates levels of mercaptopyruvate, an important source of hydrogen sulfide. Mercaptopyruvate is converted into H(2)S via the action of 3-m [...]	Interleukin 4 induced 1.	0.902
GOT1	LOC100055246	ENSECAP00000000135	ENSECAP00000017508	Aspartate aminotransferase, cytoplasmic; Biosynthesis of L-glutamate from L-aspartate or L-cysteine. Important regulator of levels of glutamate, the major excitatory neurotransmitter of the vertebrate central nervous system. Acts as a scavenger of glutamate in brain neuroprotection. The aspartate aminotransferase activity is involved in hepatic glucose synthesis during development and in adipocyte glyceroneogenesis. Using L-cysteine as substrate, regulates levels of mercaptopyruvate, an important source of hydrogen sulfide. Mercaptopyruvate is converted into H(2)S via the action of 3-m [...]	Amine oxidase.	0.905
GOT1	LOC100147151	ENSECAP00000000135	ENSECAP00000012687	Aspartate aminotransferase, cytoplasmic; Biosynthesis of L-glutamate from L-aspartate or L-cysteine. Important regulator of levels of glutamate, the major excitatory neurotransmitter of the vertebrate central nervous system. Acts as a scavenger of glutamate in brain neuroprotection. The aspartate aminotransferase activity is involved in hepatic glucose synthesis during development and in adipocyte glyceroneogenesis. Using L-cysteine as substrate, regulates levels of mercaptopyruvate, an important source of hydrogen sulfide. Mercaptopyruvate is converted into H(2)S via the action of 3-m [...]	Amine oxidase.	0.902
GOT1	MIF	ENSECAP00000000135	ENSECAP00000010567	Aspartate aminotransferase, cytoplasmic; Biosynthesis of L-glutamate from L-aspartate or L-cysteine. Important regulator of levels of glutamate, the major excitatory neurotransmitter of the vertebrate central nervous system. Acts as a scavenger of glutamate in brain neuroprotection. The aspartate aminotransferase activity is involved in hepatic glucose synthesis during development and in adipocyte glyceroneogenesis. Using L-cysteine as substrate, regulates levels of mercaptopyruvate, an important source of hydrogen sulfide. Mercaptopyruvate is converted into H(2)S via the action of 3-m [...]	Macrophage migration inhibitory factor.	0.917
GOT1	TAT	ENSECAP00000000135	ENSECAP00000034210	Aspartate aminotransferase, cytoplasmic; Biosynthesis of L-glutamate from L-aspartate or L-cysteine. Important regulator of levels of glutamate, the major excitatory neurotransmitter of the vertebrate central nervous system. Acts as a scavenger of glutamate in brain neuroprotection. The aspartate aminotransferase activity is involved in hepatic glucose synthesis during development and in adipocyte glyceroneogenesis. Using L-cysteine as substrate, regulates levels of mercaptopyruvate, an important source of hydrogen sulfide. Mercaptopyruvate is converted into H(2)S via the action of 3-m [...]	Tyrosine aminotransferase; Transaminase involved in tyrosine breakdown. Converts tyrosine to p-hydroxyphenylpyruvate.	0.950
GOT1L1	GOT1	ENSECAP00000013482	ENSECAP00000000135	Glutamic-oxaloacetic transaminase 1 like 1.	Aspartate aminotransferase, cytoplasmic; Biosynthesis of L-glutamate from L-aspartate or L-cysteine. Important regulator of levels of glutamate, the major excitatory neurotransmitter of the vertebrate central nervous system. Acts as a scavenger of glutamate in brain neuroprotection. The aspartate aminotransferase activity is involved in hepatic glucose synthesis during development and in adipocyte glyceroneogenesis. Using L-cysteine as substrate, regulates levels of mercaptopyruvate, an important source of hydrogen sulfide. Mercaptopyruvate is converted into H(2)S via the action of 3-m [...]	0.913
GOT1L1	GOT2	ENSECAP00000013482	ENSECAP00000014550	Glutamic-oxaloacetic transaminase 1 like 1.	Aspartate aminotransferase, mitochondrial; Catalyzes the irreversible transamination of the L-tryptophan metabolite L-kynurenine to form kynurenic acid (KA). Plays a key role in amino acid metabolism. Important for metabolite exchange between mitochondria and cytosol. Facilitates cellular uptake of long-chain free fatty acids (By similarity).	0.966
GOT1L1	HPD	ENSECAP00000013482	ENSECAP00000009738	Glutamic-oxaloacetic transaminase 1 like 1.	4-hydroxyphenylpyruvate dioxygenase.	0.957
GOT1L1	IL4I1	ENSECAP00000013482	ENSECAP00000015625	Glutamic-oxaloacetic transaminase 1 like 1.	Interleukin 4 induced 1.	0.900
GOT1L1	LOC100055246	ENSECAP00000013482	ENSECAP00000017508	Glutamic-oxaloacetic transaminase 1 like 1.	Amine oxidase.	0.905
GOT1L1	LOC100147151	ENSECAP00000013482	ENSECAP00000012687	Glutamic-oxaloacetic transaminase 1 like 1.	Amine oxidase.	0.902
GOT1L1	MIF	ENSECAP00000013482	ENSECAP00000010567	Glutamic-oxaloacetic transaminase 1 like 1.	Macrophage migration inhibitory factor.	0.910
GOT1L1	TAT	ENSECAP00000013482	ENSECAP00000034210	Glutamic-oxaloacetic transaminase 1 like 1.	Tyrosine aminotransferase; Transaminase involved in tyrosine breakdown. Converts tyrosine to p-hydroxyphenylpyruvate.	0.947