MIF protein (Equus caballus) - STRING interaction network

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Score

MIF

Macrophage migration inhibitory factor. (115 aa)

Predicted Functional Partners:

CD74

0.984

LOC100147151

0.889

COPS5

0.887

GOT1

0.854

HPD

0.852

TAT

0.851

GOT2

0.842

GOT1L1

0.839

DDT

0.837

IL4I1

0.805

Your Current Organism:

Equus caballus

NCBI taxonomy Id: 9796
Other names: E. caballus, Equus przewalskii f. caballus, Equus przewalskii forma caballus, domestic horse, equine, horse

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CD74	COPS5	ENSECAP00000039301	ENSECAP00000011800	CD74 molecule.	COP9 signalosome complex subunit 5-like protein.	0.428
CD74	DDT	ENSECAP00000039301	ENSECAP00000018564	CD74 molecule.	D-dopachrome tautomerase like.	0.701
CD74	MIF	ENSECAP00000039301	ENSECAP00000010567	CD74 molecule.	Macrophage migration inhibitory factor.	0.984
COPS5	CD74	ENSECAP00000011800	ENSECAP00000039301	COP9 signalosome complex subunit 5-like protein.	CD74 molecule.	0.428
COPS5	MIF	ENSECAP00000011800	ENSECAP00000010567	COP9 signalosome complex subunit 5-like protein.	Macrophage migration inhibitory factor.	0.887
DDT	CD74	ENSECAP00000018564	ENSECAP00000039301	D-dopachrome tautomerase like.	CD74 molecule.	0.701
DDT	GOT1	ENSECAP00000018564	ENSECAP00000000135	D-dopachrome tautomerase like.	Aspartate aminotransferase, cytoplasmic; Biosynthesis of L-glutamate from L-aspartate or L-cysteine. Important regulator of levels of glutamate, the major excitatory neurotransmitter of the vertebrate central nervous system. Acts as a scavenger of glutamate in brain neuroprotection. The aspartate aminotransferase activity is involved in hepatic glucose synthesis during development and in adipocyte glyceroneogenesis. Using L-cysteine as substrate, regulates levels of mercaptopyruvate, an important source of hydrogen sulfide. Mercaptopyruvate is converted into H(2)S via the action of 3-m [...]	0.770
DDT	GOT1L1	ENSECAP00000018564	ENSECAP00000013482	D-dopachrome tautomerase like.	Glutamic-oxaloacetic transaminase 1 like 1.	0.425
DDT	GOT2	ENSECAP00000018564	ENSECAP00000014550	D-dopachrome tautomerase like.	Aspartate aminotransferase, mitochondrial; Catalyzes the irreversible transamination of the L-tryptophan metabolite L-kynurenine to form kynurenic acid (KA). Plays a key role in amino acid metabolism. Important for metabolite exchange between mitochondria and cytosol. Facilitates cellular uptake of long-chain free fatty acids (By similarity).	0.760
DDT	HPD	ENSECAP00000018564	ENSECAP00000009738	D-dopachrome tautomerase like.	4-hydroxyphenylpyruvate dioxygenase.	0.789
DDT	MIF	ENSECAP00000018564	ENSECAP00000010567	D-dopachrome tautomerase like.	Macrophage migration inhibitory factor.	0.837
DDT	TAT	ENSECAP00000018564	ENSECAP00000034210	D-dopachrome tautomerase like.	Tyrosine aminotransferase; Transaminase involved in tyrosine breakdown. Converts tyrosine to p-hydroxyphenylpyruvate.	0.787
GOT1	DDT	ENSECAP00000000135	ENSECAP00000018564	Aspartate aminotransferase, cytoplasmic; Biosynthesis of L-glutamate from L-aspartate or L-cysteine. Important regulator of levels of glutamate, the major excitatory neurotransmitter of the vertebrate central nervous system. Acts as a scavenger of glutamate in brain neuroprotection. The aspartate aminotransferase activity is involved in hepatic glucose synthesis during development and in adipocyte glyceroneogenesis. Using L-cysteine as substrate, regulates levels of mercaptopyruvate, an important source of hydrogen sulfide. Mercaptopyruvate is converted into H(2)S via the action of 3-m [...]	D-dopachrome tautomerase like.	0.770
GOT1	GOT1L1	ENSECAP00000000135	ENSECAP00000013482	Aspartate aminotransferase, cytoplasmic; Biosynthesis of L-glutamate from L-aspartate or L-cysteine. Important regulator of levels of glutamate, the major excitatory neurotransmitter of the vertebrate central nervous system. Acts as a scavenger of glutamate in brain neuroprotection. The aspartate aminotransferase activity is involved in hepatic glucose synthesis during development and in adipocyte glyceroneogenesis. Using L-cysteine as substrate, regulates levels of mercaptopyruvate, an important source of hydrogen sulfide. Mercaptopyruvate is converted into H(2)S via the action of 3-m [...]	Glutamic-oxaloacetic transaminase 1 like 1.	0.908
GOT1	GOT2	ENSECAP00000000135	ENSECAP00000014550	Aspartate aminotransferase, cytoplasmic; Biosynthesis of L-glutamate from L-aspartate or L-cysteine. Important regulator of levels of glutamate, the major excitatory neurotransmitter of the vertebrate central nervous system. Acts as a scavenger of glutamate in brain neuroprotection. The aspartate aminotransferase activity is involved in hepatic glucose synthesis during development and in adipocyte glyceroneogenesis. Using L-cysteine as substrate, regulates levels of mercaptopyruvate, an important source of hydrogen sulfide. Mercaptopyruvate is converted into H(2)S via the action of 3-m [...]	Aspartate aminotransferase, mitochondrial; Catalyzes the irreversible transamination of the L-tryptophan metabolite L-kynurenine to form kynurenic acid (KA). Plays a key role in amino acid metabolism. Important for metabolite exchange between mitochondria and cytosol. Facilitates cellular uptake of long-chain free fatty acids (By similarity).	0.983
GOT1	HPD	ENSECAP00000000135	ENSECAP00000009738	Aspartate aminotransferase, cytoplasmic; Biosynthesis of L-glutamate from L-aspartate or L-cysteine. Important regulator of levels of glutamate, the major excitatory neurotransmitter of the vertebrate central nervous system. Acts as a scavenger of glutamate in brain neuroprotection. The aspartate aminotransferase activity is involved in hepatic glucose synthesis during development and in adipocyte glyceroneogenesis. Using L-cysteine as substrate, regulates levels of mercaptopyruvate, an important source of hydrogen sulfide. Mercaptopyruvate is converted into H(2)S via the action of 3-m [...]	4-hydroxyphenylpyruvate dioxygenase.	0.925
GOT1	IL4I1	ENSECAP00000000135	ENSECAP00000015625	Aspartate aminotransferase, cytoplasmic; Biosynthesis of L-glutamate from L-aspartate or L-cysteine. Important regulator of levels of glutamate, the major excitatory neurotransmitter of the vertebrate central nervous system. Acts as a scavenger of glutamate in brain neuroprotection. The aspartate aminotransferase activity is involved in hepatic glucose synthesis during development and in adipocyte glyceroneogenesis. Using L-cysteine as substrate, regulates levels of mercaptopyruvate, an important source of hydrogen sulfide. Mercaptopyruvate is converted into H(2)S via the action of 3-m [...]	Interleukin 4 induced 1.	0.812
GOT1	LOC100147151	ENSECAP00000000135	ENSECAP00000012687	Aspartate aminotransferase, cytoplasmic; Biosynthesis of L-glutamate from L-aspartate or L-cysteine. Important regulator of levels of glutamate, the major excitatory neurotransmitter of the vertebrate central nervous system. Acts as a scavenger of glutamate in brain neuroprotection. The aspartate aminotransferase activity is involved in hepatic glucose synthesis during development and in adipocyte glyceroneogenesis. Using L-cysteine as substrate, regulates levels of mercaptopyruvate, an important source of hydrogen sulfide. Mercaptopyruvate is converted into H(2)S via the action of 3-m [...]	Amine oxidase.	0.894
GOT1	MIF	ENSECAP00000000135	ENSECAP00000010567	Aspartate aminotransferase, cytoplasmic; Biosynthesis of L-glutamate from L-aspartate or L-cysteine. Important regulator of levels of glutamate, the major excitatory neurotransmitter of the vertebrate central nervous system. Acts as a scavenger of glutamate in brain neuroprotection. The aspartate aminotransferase activity is involved in hepatic glucose synthesis during development and in adipocyte glyceroneogenesis. Using L-cysteine as substrate, regulates levels of mercaptopyruvate, an important source of hydrogen sulfide. Mercaptopyruvate is converted into H(2)S via the action of 3-m [...]	Macrophage migration inhibitory factor.	0.854
GOT1	TAT	ENSECAP00000000135	ENSECAP00000034210	Aspartate aminotransferase, cytoplasmic; Biosynthesis of L-glutamate from L-aspartate or L-cysteine. Important regulator of levels of glutamate, the major excitatory neurotransmitter of the vertebrate central nervous system. Acts as a scavenger of glutamate in brain neuroprotection. The aspartate aminotransferase activity is involved in hepatic glucose synthesis during development and in adipocyte glyceroneogenesis. Using L-cysteine as substrate, regulates levels of mercaptopyruvate, an important source of hydrogen sulfide. Mercaptopyruvate is converted into H(2)S via the action of 3-m [...]	Tyrosine aminotransferase; Transaminase involved in tyrosine breakdown. Converts tyrosine to p-hydroxyphenylpyruvate.	0.942