HSF2 protein (Equus caballus) - STRING interaction network

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Score

HSF2

Heat shock transcription factor 2. (535 aa)

Predicted Functional Partners:

VASH2

0.696

HSP90AB1

0.662

HSP90AA1

0.662

HSF1

0.654

MBD6

0.648

TSC1

0.632

TRAP1

0.632

PTGES3

0.628

RBM44

0.624

TMEM184C

0.596

Your Current Organism:

Equus caballus

NCBI taxonomy Id: 9796
Other names: E. caballus, Equus przewalskii f. caballus, Equus przewalskii forma caballus, domestic horse, equine, horse

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
HSF1	HSF2	ENSECAP00000001298	ENSECAP00000010575	Heat shock transcription factor 1.	Heat shock transcription factor 2.	0.654
HSF1	HSP90AA1	ENSECAP00000001298	ENSECAP00000025926	Heat shock transcription factor 1.	Heat shock protein HSP 90-alpha; Molecular chaperone that promotes the maturation, structural maintenance and proper regulation of specific target proteins involved for instance in cell cycle control and signal transduction. Undergoes a functional cycle that is linked to its ATPase activity which is essential for its chaperone activity. This cycle probably induces conformational changes in the client proteins, thereby causing their activation. Interacts dynamically with various co-chaperones that modulate its substrate recognition, ATPase cycle and chaperone function. Engages with a ra [...]	0.760
HSF1	HSP90AB1	ENSECAP00000001298	ENSECAP00000006887	Heat shock transcription factor 1.	Heat shock protein HSP 90-beta; Molecular chaperone that promotes the maturation, structural maintenance and proper regulation of specific target proteins involved for instance in cell cycle control and signal transduction. Undergoes a functional cycle that is linked to its ATPase activity. This cycle probably induces conformational changes in the client proteins, thereby causing their activation. Interacts dynamically with various co- chaperones that modulate its substrate recognition, ATPase cycle and chaperone function. Engages with a range of client protein classes via its interact [...]	0.760
HSF1	PTGES3	ENSECAP00000001298	ENSECAP00000011047	Heat shock transcription factor 1.	Prostaglandin E synthase 3.	0.908
HSF1	TRAP1	ENSECAP00000001298	ENSECAP00000037781	Heat shock transcription factor 1.	TNF receptor associated protein 1.	0.649
HSF1	TSC1	ENSECAP00000001298	ENSECAP00000008097	Heat shock transcription factor 1.	TSC complex subunit 1.	0.754
HSF2	HSF1	ENSECAP00000010575	ENSECAP00000001298	Heat shock transcription factor 2.	Heat shock transcription factor 1.	0.654
HSF2	HSP90AA1	ENSECAP00000010575	ENSECAP00000025926	Heat shock transcription factor 2.	Heat shock protein HSP 90-alpha; Molecular chaperone that promotes the maturation, structural maintenance and proper regulation of specific target proteins involved for instance in cell cycle control and signal transduction. Undergoes a functional cycle that is linked to its ATPase activity which is essential for its chaperone activity. This cycle probably induces conformational changes in the client proteins, thereby causing their activation. Interacts dynamically with various co-chaperones that modulate its substrate recognition, ATPase cycle and chaperone function. Engages with a ra [...]	0.662
HSF2	HSP90AB1	ENSECAP00000010575	ENSECAP00000006887	Heat shock transcription factor 2.	Heat shock protein HSP 90-beta; Molecular chaperone that promotes the maturation, structural maintenance and proper regulation of specific target proteins involved for instance in cell cycle control and signal transduction. Undergoes a functional cycle that is linked to its ATPase activity. This cycle probably induces conformational changes in the client proteins, thereby causing their activation. Interacts dynamically with various co- chaperones that modulate its substrate recognition, ATPase cycle and chaperone function. Engages with a range of client protein classes via its interact [...]	0.662
HSF2	MBD6	ENSECAP00000010575	ENSECAP00000022834	Heat shock transcription factor 2.	Methyl-CpG binding domain protein 6.	0.648
HSF2	PTGES3	ENSECAP00000010575	ENSECAP00000011047	Heat shock transcription factor 2.	Prostaglandin E synthase 3.	0.628
HSF2	RBM44	ENSECAP00000010575	ENSECAP00000003713	Heat shock transcription factor 2.	RNA binding motif protein 44.	0.624
HSF2	TMEM184C	ENSECAP00000010575	ENSECAP00000017221	Heat shock transcription factor 2.	Transmembrane protein 184C.	0.596
HSF2	TRAP1	ENSECAP00000010575	ENSECAP00000037781	Heat shock transcription factor 2.	TNF receptor associated protein 1.	0.632
HSF2	TSC1	ENSECAP00000010575	ENSECAP00000008097	Heat shock transcription factor 2.	TSC complex subunit 1.	0.632
HSF2	VASH2	ENSECAP00000010575	ENSECAP00000013471	Heat shock transcription factor 2.	Vasohibin 2.	0.696
HSP90AA1	HSF1	ENSECAP00000025926	ENSECAP00000001298	Heat shock protein HSP 90-alpha; Molecular chaperone that promotes the maturation, structural maintenance and proper regulation of specific target proteins involved for instance in cell cycle control and signal transduction. Undergoes a functional cycle that is linked to its ATPase activity which is essential for its chaperone activity. This cycle probably induces conformational changes in the client proteins, thereby causing their activation. Interacts dynamically with various co-chaperones that modulate its substrate recognition, ATPase cycle and chaperone function. Engages with a ra [...]	Heat shock transcription factor 1.	0.760
HSP90AA1	HSF2	ENSECAP00000025926	ENSECAP00000010575	Heat shock protein HSP 90-alpha; Molecular chaperone that promotes the maturation, structural maintenance and proper regulation of specific target proteins involved for instance in cell cycle control and signal transduction. Undergoes a functional cycle that is linked to its ATPase activity which is essential for its chaperone activity. This cycle probably induces conformational changes in the client proteins, thereby causing their activation. Interacts dynamically with various co-chaperones that modulate its substrate recognition, ATPase cycle and chaperone function. Engages with a ra [...]	Heat shock transcription factor 2.	0.662
HSP90AA1	HSP90AB1	ENSECAP00000025926	ENSECAP00000006887	Heat shock protein HSP 90-alpha; Molecular chaperone that promotes the maturation, structural maintenance and proper regulation of specific target proteins involved for instance in cell cycle control and signal transduction. Undergoes a functional cycle that is linked to its ATPase activity which is essential for its chaperone activity. This cycle probably induces conformational changes in the client proteins, thereby causing their activation. Interacts dynamically with various co-chaperones that modulate its substrate recognition, ATPase cycle and chaperone function. Engages with a ra [...]	Heat shock protein HSP 90-beta; Molecular chaperone that promotes the maturation, structural maintenance and proper regulation of specific target proteins involved for instance in cell cycle control and signal transduction. Undergoes a functional cycle that is linked to its ATPase activity. This cycle probably induces conformational changes in the client proteins, thereby causing their activation. Interacts dynamically with various co- chaperones that modulate its substrate recognition, ATPase cycle and chaperone function. Engages with a range of client protein classes via its interact [...]	0.904
HSP90AA1	PTGES3	ENSECAP00000025926	ENSECAP00000011047	Heat shock protein HSP 90-alpha; Molecular chaperone that promotes the maturation, structural maintenance and proper regulation of specific target proteins involved for instance in cell cycle control and signal transduction. Undergoes a functional cycle that is linked to its ATPase activity which is essential for its chaperone activity. This cycle probably induces conformational changes in the client proteins, thereby causing their activation. Interacts dynamically with various co-chaperones that modulate its substrate recognition, ATPase cycle and chaperone function. Engages with a ra [...]	Prostaglandin E synthase 3.	0.993