STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PHOX2BPaired like homeobox 2B. (310 aa)    
Predicted Functional Partners:
TH
Tyrosine hydroxylase.
   
  
 0.926
DBH
Soluble dopamine beta-hydroxylase; Conversion of dopamine to noradrenaline. Belongs to the copper type II ascorbate-dependent monooxygenase family.
   
  
 0.754
SOX10
SRY-box transcription factor 10.
   
  
 0.719
MYCN
MYCN proto-oncogene, bHLH transcription factor.
      
 0.660
HAND2
Heart and neural crest derivatives expressed 2.
   
 
 0.656
ATOH1
Atonal bHLH transcription factor 1.
      
 0.649
NMB
Neuromedin B.
      
 0.632
PNMT
Phenylethanolamine N-methyltransferase.
   
  
 0.612
GATA3
GATA binding protein 3.
      
 0.596
ASCL1
Achaete-scute family bHLH transcription factor 1.
   
 
 0.589
Your Current Organism:
Equus caballus
NCBI taxonomy Id: 9796
Other names: E. caballus, Equus przewalskii f. caballus, Equus przewalskii forma caballus, domestic horse, equine, horse
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.