Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
TMEM108Transmembrane protein 108. (647 aa)    
Predicted Functional Partners:
SUSD5
Sushi domain containing 5.
      
 0.709
TM4SF5
Transmembrane 4 L six family member 5.
      
 0.639
UPK3B
Uroplakin 3B.
      
 0.638
CACHD1
Cache domain containing 1.
   
  
 0.637
PCDH20
Uncharacterized protein.
      
 0.630
SEZ6L
Seizure related 6 homolog like.
      
 0.630
BACE2
Beta-secretase 2; Belongs to the peptidase A1 family.
   
  
 0.564
ASTE1
Asteroid homolog 1.
      
 0.554
GUCA2A
Guanylate cyclase activator 2A.
      
 0.551
ADAM22
ADAM metallopeptidase domain 22.
      
 0.525
Your Current Organism:
Equus caballus
NCBI taxonomy Id: 9796
Other names: E. caballus, Equus przewalskii f. caballus, Equus przewalskii forma caballus, domestic horse, equine, horse
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