STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SMPD1Sphingomyelin phosphodiesterase 1. (824 aa)    
Predicted Functional Partners:
SMPD2
Sphingomyelin phosphodiesterase 2.
   
 
 0.985
SGMS2
Sphingomyelin synthase 2.
     
 0.982
UGCG
UDP-glucose ceramide glucosyltransferase.
     
 0.975
SMPD4
Sphingomyelin phosphodiesterase 4.
     
 0.973
CERS2
Ceramide synthase 2.
   
 
 0.971
CERK
Ceramide kinase.
    
 0.969
GBA
Glucosylceramidase.
   
 
 0.964
CERS6
Ceramide synthase 6.
     
 0.961
LOC111770943
N-acylsphingosine amidohydrolase 1; Belongs to the acid ceramidase family.
   
 0.959
DEGS1
Delta 4-desaturase, sphingolipid 1.
     
 0.957
Your Current Organism:
Equus caballus
NCBI taxonomy Id: 9796
Other names: E. caballus, Equus przewalskii f. caballus, Equus przewalskii forma caballus, domestic horse, equine, horse
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.