STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
NOTCH4Notch receptor 4. (2021 aa)    
Predicted Functional Partners:
DLL4
Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.
   
0.997
JAG1
Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.
    
0.997
JAG2
Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.
    
0.996
RBPJ
Recombination signal binding protein for immunoglobulin kappa J region.
    
 0.995
DLL3
Delta like canonical Notch ligand 3.
   
 
0.992
DLL1
Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.
   
0.991
RBPJL
Recombination signal binding protein for immunoglobulin kappa J region like.
    
 0.962
MAML2
Mastermind like transcriptional coactivator 2.
    
 0.961
MAML1
Mastermind like transcriptional coactivator 1.
    
 0.961
NUMB
NUMB endocytic adaptor protein.
    
 0.945
Your Current Organism:
Equus caballus
NCBI taxonomy Id: 9796
Other names: E. caballus, Equus przewalskii f. caballus, Equus przewalskii forma caballus, domestic horse, equine, horse
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