STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
APLFAprataxin and PNKP like factor. (512 aa)    
Predicted Functional Partners:
APTX
Aprataxin.
      
 0.932
XRCC5
X-ray repair cross complementing 5.
    
 
 0.913
XRCC6
X-ray repair cross complementing 6.
    
 
 0.886
CHFR
Checkpoint with forkhead and ring finger domains.
      
 0.868
LIG4
DNA ligase.
    
 
 0.858
XRCC1
X-ray repair cross complementing 1.
   
 
 0.853
KRT222
IF rod domain-containing protein; Belongs to the intermediate filament family.
   
  
 0.845
ZBTB24
Zinc finger and BTB domain containing 24.
    
 
 0.828
PARP3
Poly [ADP-ribose] polymerase.
    
 
 0.819
PNKP
Polynucleotide kinase 3'-phosphatase.
      
 0.800
Your Current Organism:
Equus caballus
NCBI taxonomy Id: 9796
Other names: E. caballus, Equus przewalskii f. caballus, Equus przewalskii forma caballus, domestic horse, equine, horse
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.