STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DLL4Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (685 aa)    
Predicted Functional Partners:
NOTCH1
Notch receptor 1.
   
0.999
NOTCH4
Notch receptor 4.
   
0.997
NOTCH3
Notch receptor 3.
    
0.995
NOTCH2
Notch receptor 2.
    
0.995
DLL1
Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.
  
 
0.943
DLL3
Delta like canonical Notch ligand 3.
     
0.919
HEY1
Hes related family bHLH transcription factor with YRPW motif 1.
   
 0.850
RBPJ
Recombination signal binding protein for immunoglobulin kappa J region.
    
 0.816
EMCN
Endomucin.
   
  
 0.789
HEYL
Hes related family bHLH transcription factor with YRPW motif like.
    
 0.783
Your Current Organism:
Equus caballus
NCBI taxonomy Id: 9796
Other names: E. caballus, Equus przewalskii f. caballus, Equus przewalskii forma caballus, domestic horse, equine, horse
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.