node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
INS | KIT | ENSECAP00000022114 | ENSECAP00000011188 | Insulin A chain; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. | KIT proto-oncogene, receptor tyrosine kinase; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. | 0.951 |
INS | KITLG | ENSECAP00000022114 | ENSECAP00000000163 | Insulin A chain; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. | Processed kit ligand; Stimulates the proliferation of mast cells. Able to augment the proliferation of both myeloid and lymphoid hematopoietic progenitors in bone marrow culture. Mediates also cell-cell adhesion. Acts synergistically with other cytokines, probably interleukins (By similarity); Belongs to the SCF family. | 0.645 |
INS | KRAS | ENSECAP00000022114 | ENSECAP00000017062 | Insulin A chain; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. | KRAS proto-oncogene, GTPase. | 0.601 |
INS | PIK3CA | ENSECAP00000022114 | ENSECAP00000013092 | Insulin A chain; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. | 0.656 |
INS | PIK3R1 | ENSECAP00000022114 | ENSECAP00000017836 | Insulin A chain; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. | Phosphoinositide-3-kinase regulatory subunit 1. | 0.421 |
INS | STAT3 | ENSECAP00000022114 | ENSECAP00000036035 | Insulin A chain; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. | Signal transducer and activator of transcription. | 0.742 |
KIT | INS | ENSECAP00000011188 | ENSECAP00000022114 | KIT proto-oncogene, receptor tyrosine kinase; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. | Insulin A chain; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. | 0.951 |
KIT | KITLG | ENSECAP00000011188 | ENSECAP00000000163 | KIT proto-oncogene, receptor tyrosine kinase; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. | Processed kit ligand; Stimulates the proliferation of mast cells. Able to augment the proliferation of both myeloid and lymphoid hematopoietic progenitors in bone marrow culture. Mediates also cell-cell adhesion. Acts synergistically with other cytokines, probably interleukins (By similarity); Belongs to the SCF family. | 0.999 |
KIT | KRAS | ENSECAP00000011188 | ENSECAP00000017062 | KIT proto-oncogene, receptor tyrosine kinase; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. | KRAS proto-oncogene, GTPase. | 0.960 |
KIT | LOC100052122 | ENSECAP00000011188 | ENSECAP00000031451 | KIT proto-oncogene, receptor tyrosine kinase; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. | Uncharacterized protein. | 0.963 |
KIT | NRAS | ENSECAP00000011188 | ENSECAP00000011720 | KIT proto-oncogene, receptor tyrosine kinase; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. | NRAS proto-oncogene, GTPase. | 0.972 |
KIT | PIK3CA | ENSECAP00000011188 | ENSECAP00000013092 | KIT proto-oncogene, receptor tyrosine kinase; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. | 0.967 |
KIT | PIK3R1 | ENSECAP00000011188 | ENSECAP00000017836 | KIT proto-oncogene, receptor tyrosine kinase; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. | Phosphoinositide-3-kinase regulatory subunit 1. | 0.979 |
KIT | PIK3R2 | ENSECAP00000011188 | ENSECAP00000023307 | KIT proto-oncogene, receptor tyrosine kinase; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. | Uncharacterized protein. | 0.963 |
KIT | PTPN11 | ENSECAP00000011188 | ENSECAP00000022175 | KIT proto-oncogene, receptor tyrosine kinase; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. | Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. | 0.976 |
KIT | STAT3 | ENSECAP00000011188 | ENSECAP00000036035 | KIT proto-oncogene, receptor tyrosine kinase; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. | Signal transducer and activator of transcription. | 0.963 |
KITLG | INS | ENSECAP00000000163 | ENSECAP00000022114 | Processed kit ligand; Stimulates the proliferation of mast cells. Able to augment the proliferation of both myeloid and lymphoid hematopoietic progenitors in bone marrow culture. Mediates also cell-cell adhesion. Acts synergistically with other cytokines, probably interleukins (By similarity); Belongs to the SCF family. | Insulin A chain; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. | 0.645 |
KITLG | KIT | ENSECAP00000000163 | ENSECAP00000011188 | Processed kit ligand; Stimulates the proliferation of mast cells. Able to augment the proliferation of both myeloid and lymphoid hematopoietic progenitors in bone marrow culture. Mediates also cell-cell adhesion. Acts synergistically with other cytokines, probably interleukins (By similarity); Belongs to the SCF family. | KIT proto-oncogene, receptor tyrosine kinase; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. | 0.999 |
KITLG | LOC100052122 | ENSECAP00000000163 | ENSECAP00000031451 | Processed kit ligand; Stimulates the proliferation of mast cells. Able to augment the proliferation of both myeloid and lymphoid hematopoietic progenitors in bone marrow culture. Mediates also cell-cell adhesion. Acts synergistically with other cytokines, probably interleukins (By similarity); Belongs to the SCF family. | Uncharacterized protein. | 0.535 |
KITLG | NRAS | ENSECAP00000000163 | ENSECAP00000011720 | Processed kit ligand; Stimulates the proliferation of mast cells. Able to augment the proliferation of both myeloid and lymphoid hematopoietic progenitors in bone marrow culture. Mediates also cell-cell adhesion. Acts synergistically with other cytokines, probably interleukins (By similarity); Belongs to the SCF family. | NRAS proto-oncogene, GTPase. | 0.421 |