STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ABCA3ATP binding cassette subfamily A member 3. (1704 aa)    
Predicted Functional Partners:
SFTPB
Surfactant protein B.
      
 0.848
SFTPC
Surfactant protein C.
      
 0.835
SBNO2
Strawberry notch homolog 2.
      
 0.650
LPCAT1
Lysophosphatidylcholine acyltransferase 1.
   
 
 0.603
SFTPA1
Pulmonary surfactant-associated protein A; In presence of calcium ions, it binds to surfactant phospholipids and contributes to lower the surface tension at the air- liquid interface in the alveoli of the mammalian lung and is essential for normal respiration. Enhances the expression of MYO18A/SP-R210 on alveolar macrophages.
      
 0.583
AQP5
Aquaporin 5; Belongs to the MIP/aquaporin (TC 1.A.8) family.
   
  
 0.557
PCYT1A
Phosphate cytidylyltransferase 1, choline, alpha.
      
 0.503
ABCF3
ATP binding cassette subfamily F member 3.
   
 
 0.501
FOXJ1
Forkhead box J1.
    
 0.491
HOPX
Homeobox domain-containing protein.
   
  
 0.479
Your Current Organism:
Equus caballus
NCBI taxonomy Id: 9796
Other names: E. caballus, Equus przewalskii f. caballus, Equus przewalskii forma caballus, domestic horse, equine, horse
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