STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
HSD11B2Hydroxysteroid 11-beta dehydrogenase 2. (405 aa)    
Predicted Functional Partners:
HSD11B1
Hydroxysteroid 11-beta dehydrogenase 1.
  
 
0.995
CYP21A2
Cytochrome P450 family 21 subfamily A member 2; Belongs to the cytochrome P450 family.
   
 
 0.952
LOC100063645
Uncharacterized protein; Belongs to the cytochrome P450 family.
   
 
 0.933
LOC100063612
Uncharacterized protein; Belongs to the cytochrome P450 family.
   
 
 0.933
HAO2
3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase; 3-beta-HSD is a bifunctional enzyme, that catalyzes the oxidative conversion of Delta(5)-ene-3-beta-hydroxy steroid, and the oxidative conversion of ketosteroids. The 3-beta-HSD enzymatic system plays a crucial role in the biosynthesis of all classes of hormonal steroids.
   
 
 0.929
AKR1D1
Aldo-keto reductase family 1 member D1.
   
 
 0.919
NR3C1
Nuclear receptor subfamily 3 group C member 1.
    
 
 0.715
NR3C2
Nuclear receptor subfamily 3 group C member 2.
   
 
 0.681
SCNN1G
Sodium channel epithelial 1 gamma subunit; Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family.
   
  
 0.629
LRPAP1
LDL receptor related protein associated protein 1.
      
 0.617
Your Current Organism:
Equus caballus
NCBI taxonomy Id: 9796
Other names: E. caballus, Equus przewalskii f. caballus, Equus przewalskii forma caballus, domestic horse, equine, horse
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.