STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SHOC1Shortage in chiasmata 1. (1442 aa)    
Predicted Functional Partners:
RNF212
RING-type domain-containing protein.
      
 0.907
TEX11
Testis expressed 11.
   
 
 0.894
MSH4
DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR).
   
  
 0.847
RNF212B
Ring finger protein 212B.
      
 0.800
REC8
REC8 meiotic recombination protein.
   
  
 0.762
MCMDC2
Minichromosome maintenance domain containing 2.
      
 0.738
SPO11
SPO11 initiator of meiotic double stranded breaks.
   
  
 0.600
STAG3
Stromal antigen 3.
      
 0.575
DMC1
Meiotic recombination protein; May participate in meiotic recombination, specifically in homologous strand assimilation, which is required for the resolution of meiotic double-strand breaks; Belongs to the RecA family. DMC1 subfamily.
      
 0.572
HFM1
Helicase for meiosis 1.
      
 0.569
Your Current Organism:
Equus caballus
NCBI taxonomy Id: 9796
Other names: E. caballus, Equus przewalskii f. caballus, Equus przewalskii forma caballus, domestic horse, equine, horse
Server load: low (18%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.