node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
DNAJA4 | GET3 | ENSECAP00000021233 | ENSECAP00000005353 | DnaJ heat shock protein family (Hsp40) member A4. | ATPase GET3; ATPase required for the post-translational delivery of tail- anchored (TA) proteins to the endoplasmic reticulum. Recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol. This complex then targets to the endoplasmic reticulum by membrane-bound receptors, where the tail-anchored protein is released for insertion. This process is regulated by ATP binding and hydrolysis. ATP binding drives the homodimer towards the closed dimer state, facilitating recognition of newly synthesized TA membrane proteins. ATP hydrolysis is required for insertion. S [...] | 0.631 |
DNAJA4 | LRRC4B | ENSECAP00000021233 | ENSECAP00000012235 | DnaJ heat shock protein family (Hsp40) member A4. | Leucine rich repeat containing 4B. | 0.690 |
DNAJA4 | NAA25 | ENSECAP00000021233 | ENSECAP00000007188 | DnaJ heat shock protein family (Hsp40) member A4. | N(alpha)-acetyltransferase 25, NatB auxiliary subunit. | 0.677 |
DNAJA4 | PHAX | ENSECAP00000021233 | ENSECAP00000033147 | DnaJ heat shock protein family (Hsp40) member A4. | Phosphorylated adaptor for RNA export. | 0.648 |
DNAJA4 | SGTB | ENSECAP00000021233 | ENSECAP00000002381 | DnaJ heat shock protein family (Hsp40) member A4. | Small glutamine rich tetratricopeptide repeat containing beta. | 0.746 |
GET3 | DNAJA4 | ENSECAP00000005353 | ENSECAP00000021233 | ATPase GET3; ATPase required for the post-translational delivery of tail- anchored (TA) proteins to the endoplasmic reticulum. Recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol. This complex then targets to the endoplasmic reticulum by membrane-bound receptors, where the tail-anchored protein is released for insertion. This process is regulated by ATP binding and hydrolysis. ATP binding drives the homodimer towards the closed dimer state, facilitating recognition of newly synthesized TA membrane proteins. ATP hydrolysis is required for insertion. S [...] | DnaJ heat shock protein family (Hsp40) member A4. | 0.631 |
GET3 | LRRC4B | ENSECAP00000005353 | ENSECAP00000012235 | ATPase GET3; ATPase required for the post-translational delivery of tail- anchored (TA) proteins to the endoplasmic reticulum. Recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol. This complex then targets to the endoplasmic reticulum by membrane-bound receptors, where the tail-anchored protein is released for insertion. This process is regulated by ATP binding and hydrolysis. ATP binding drives the homodimer towards the closed dimer state, facilitating recognition of newly synthesized TA membrane proteins. ATP hydrolysis is required for insertion. S [...] | Leucine rich repeat containing 4B. | 0.704 |
GET3 | NAA25 | ENSECAP00000005353 | ENSECAP00000007188 | ATPase GET3; ATPase required for the post-translational delivery of tail- anchored (TA) proteins to the endoplasmic reticulum. Recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol. This complex then targets to the endoplasmic reticulum by membrane-bound receptors, where the tail-anchored protein is released for insertion. This process is regulated by ATP binding and hydrolysis. ATP binding drives the homodimer towards the closed dimer state, facilitating recognition of newly synthesized TA membrane proteins. ATP hydrolysis is required for insertion. S [...] | N(alpha)-acetyltransferase 25, NatB auxiliary subunit. | 0.715 |
GET3 | PHAX | ENSECAP00000005353 | ENSECAP00000033147 | ATPase GET3; ATPase required for the post-translational delivery of tail- anchored (TA) proteins to the endoplasmic reticulum. Recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol. This complex then targets to the endoplasmic reticulum by membrane-bound receptors, where the tail-anchored protein is released for insertion. This process is regulated by ATP binding and hydrolysis. ATP binding drives the homodimer towards the closed dimer state, facilitating recognition of newly synthesized TA membrane proteins. ATP hydrolysis is required for insertion. S [...] | Phosphorylated adaptor for RNA export. | 0.697 |
GET3 | SGTB | ENSECAP00000005353 | ENSECAP00000002381 | ATPase GET3; ATPase required for the post-translational delivery of tail- anchored (TA) proteins to the endoplasmic reticulum. Recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol. This complex then targets to the endoplasmic reticulum by membrane-bound receptors, where the tail-anchored protein is released for insertion. This process is regulated by ATP binding and hydrolysis. ATP binding drives the homodimer towards the closed dimer state, facilitating recognition of newly synthesized TA membrane proteins. ATP hydrolysis is required for insertion. S [...] | Small glutamine rich tetratricopeptide repeat containing beta. | 0.884 |
LRRC4B | DNAJA4 | ENSECAP00000012235 | ENSECAP00000021233 | Leucine rich repeat containing 4B. | DnaJ heat shock protein family (Hsp40) member A4. | 0.690 |
LRRC4B | GET3 | ENSECAP00000012235 | ENSECAP00000005353 | Leucine rich repeat containing 4B. | ATPase GET3; ATPase required for the post-translational delivery of tail- anchored (TA) proteins to the endoplasmic reticulum. Recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol. This complex then targets to the endoplasmic reticulum by membrane-bound receptors, where the tail-anchored protein is released for insertion. This process is regulated by ATP binding and hydrolysis. ATP binding drives the homodimer towards the closed dimer state, facilitating recognition of newly synthesized TA membrane proteins. ATP hydrolysis is required for insertion. S [...] | 0.704 |
LRRC4B | NAA25 | ENSECAP00000012235 | ENSECAP00000007188 | Leucine rich repeat containing 4B. | N(alpha)-acetyltransferase 25, NatB auxiliary subunit. | 0.776 |
LRRC4B | NTNG1 | ENSECAP00000012235 | ENSECAP00000052279 | Leucine rich repeat containing 4B. | Netrin G1. | 0.753 |
LRRC4B | PCDHB3 | ENSECAP00000012235 | ENSECAP00000050377 | Leucine rich repeat containing 4B. | Protocadherin beta 3. | 0.835 |
LRRC4B | PHAX | ENSECAP00000012235 | ENSECAP00000033147 | Leucine rich repeat containing 4B. | Phosphorylated adaptor for RNA export. | 0.723 |
LRRC4B | PTPRF | ENSECAP00000012235 | ENSECAP00000037312 | Leucine rich repeat containing 4B. | Protein tyrosine phosphatase receptor type F. | 0.981 |
LRRC4B | PTPRS | ENSECAP00000012235 | ENSECAP00000053293 | Leucine rich repeat containing 4B. | Protein tyrosine phosphatase receptor type S. | 0.679 |
LRRC4B | SGTB | ENSECAP00000012235 | ENSECAP00000002381 | Leucine rich repeat containing 4B. | Small glutamine rich tetratricopeptide repeat containing beta. | 0.768 |
LRRC4B | SYT3 | ENSECAP00000012235 | ENSECAP00000013610 | Leucine rich repeat containing 4B. | Synaptotagmin 3. | 0.699 |