STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TNFRSF11BTumor necrosis factor receptor superfamily member 11B; Acts as decoy receptor for TNFSF11/RANKL and thereby neutralizes its function in osteoclastogenesis. (401 aa)    
Predicted Functional Partners:
TNFSF11
Tumor necrosis factor ligand superfamily member.
   
 0.998
TGFB2
Transforming growth factor beta; Belongs to the TGF-beta family.
   
  
 0.725
TNFSF18
Tumor necrosis factor ligand 2A.
   
 0.718
IBSP
Integrin binding sialoprotein.
   
  
 0.621
FOSL1
FOS like 1, AP-1 transcription factor subunit.
      
 0.619
CTSK
Cathepsin K; Belongs to the peptidase C1 family.
   
  
 0.615
TNFSF15
Tumor necrosis factor ligand 1B.
   
 0.605
BTLA
B and T lymphocyte associated.
   
 0.590
TNFSF14
Tumor necrosis factor ligand 1D.
   
 0.590
IFNGR2
Interferon gamma receptor 2.
   
  
 0.585
Your Current Organism:
Equus caballus
NCBI taxonomy Id: 9796
Other names: E. caballus, Equus przewalskii f. caballus, Equus przewalskii forma caballus, domestic horse, equine, horse
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.