STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ACAP2ArfGAP with coiled-coil, ankyrin repeat and PH domains 2. (841 aa)    
Predicted Functional Partners:
DENND6B
DENN domain containing 6B.
      
 0.900
RAB35
RAB35, member RAS oncogene family.
    
 
 0.891
OCRL
OCRL inositol polyphosphate-5-phosphatase.
    
 
 0.891
MICAL1
Microtubule associated monooxygenase, calponin and LIM domain containing 1.
   
  
 0.851
ARF6
ADP ribosylation factor 6; Belongs to the small GTPase superfamily. Arf family.
    
 0.807
TBC1D10A
TBC1 domain family member 10A.
   
  
 0.776
RUSC2
RUN and SH3 domain containing 2.
      
 0.770
DENND1B
DENN domain containing 1B.
   
  
 0.722
DENND1A
DENN domain containing 1A.
   
  
 0.718
DDHD1
DDHD domain containing 1.
      
 0.716
Your Current Organism:
Equus caballus
NCBI taxonomy Id: 9796
Other names: E. caballus, Equus przewalskii f. caballus, Equus przewalskii forma caballus, domestic horse, equine, horse
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.