SERPINA6 protein (Equus caballus) - STRING interaction network

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Score

SERPINA6

Serpin family A member 6; Belongs to the serpin family. (430 aa)

Predicted Functional Partners:

ALB

0.659

LOC100061639

0.651

SPINK9

0.604

F2

0.600

HPX

0.585

FRMD5

0.584

SYPL2

0.568

POMC

0.555

SERPINC1

0.540

LOC100061763

0.532

Your Current Organism:

Equus caballus

NCBI taxonomy Id: 9796
Other names: E. caballus, Equus przewalskii f. caballus, Equus przewalskii forma caballus, domestic horse, equine, horse

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ALB	F2	ENSECAP00000041304	ENSECAP00000009701	Serum albumin; Serum albumin, the main protein of plasma, has a good binding capacity for water, Ca(2+), Na(+), K(+), fatty acids, hormones, bilirubin and drugs. Its main function is the regulation of the colloidal osmotic pressure of blood. Major zinc transporter in plasma, typically binds about 80% of all plasma zinc (By similarity). Major calcium and magnesium transporter in plasma, binds approximately 45% of circulating calcium and magnesium in plasma (By similarity). Potentially has more than two calcium-binding sites and might additionally bind calcium in a non-specific manner (B [...]	Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family.	0.913
ALB	HPX	ENSECAP00000041304	ENSECAP00000014242	Serum albumin; Serum albumin, the main protein of plasma, has a good binding capacity for water, Ca(2+), Na(+), K(+), fatty acids, hormones, bilirubin and drugs. Its main function is the regulation of the colloidal osmotic pressure of blood. Major zinc transporter in plasma, typically binds about 80% of all plasma zinc (By similarity). Major calcium and magnesium transporter in plasma, binds approximately 45% of circulating calcium and magnesium in plasma (By similarity). Potentially has more than two calcium-binding sites and might additionally bind calcium in a non-specific manner (B [...]	Hemopexin; Binds heme and transports it to the liver for breakdown and iron recovery, after which the free hemopexin returns to the circulation.	0.757
ALB	POMC	ENSECAP00000041304	ENSECAP00000013923	Serum albumin; Serum albumin, the main protein of plasma, has a good binding capacity for water, Ca(2+), Na(+), K(+), fatty acids, hormones, bilirubin and drugs. Its main function is the regulation of the colloidal osmotic pressure of blood. Major zinc transporter in plasma, typically binds about 80% of all plasma zinc (By similarity). Major calcium and magnesium transporter in plasma, binds approximately 45% of circulating calcium and magnesium in plasma (By similarity). Potentially has more than two calcium-binding sites and might additionally bind calcium in a non-specific manner (B [...]	Melanotropin beta; MSH (melanocyte-stimulating hormone) increases the pigmentation of skin by increasing melanin production in melanocytes; Belongs to the POMC family.	0.740
ALB	SERPINA6	ENSECAP00000041304	ENSECAP00000012843	Serum albumin; Serum albumin, the main protein of plasma, has a good binding capacity for water, Ca(2+), Na(+), K(+), fatty acids, hormones, bilirubin and drugs. Its main function is the regulation of the colloidal osmotic pressure of blood. Major zinc transporter in plasma, typically binds about 80% of all plasma zinc (By similarity). Major calcium and magnesium transporter in plasma, binds approximately 45% of circulating calcium and magnesium in plasma (By similarity). Potentially has more than two calcium-binding sites and might additionally bind calcium in a non-specific manner (B [...]	Serpin family A member 6; Belongs to the serpin family.	0.659
ALB	SERPINC1	ENSECAP00000041304	ENSECAP00000012335	Serum albumin; Serum albumin, the main protein of plasma, has a good binding capacity for water, Ca(2+), Na(+), K(+), fatty acids, hormones, bilirubin and drugs. Its main function is the regulation of the colloidal osmotic pressure of blood. Major zinc transporter in plasma, typically binds about 80% of all plasma zinc (By similarity). Major calcium and magnesium transporter in plasma, binds approximately 45% of circulating calcium and magnesium in plasma (By similarity). Potentially has more than two calcium-binding sites and might additionally bind calcium in a non-specific manner (B [...]	Serpin family C member 1; Belongs to the serpin family.	0.609
F2	ALB	ENSECAP00000009701	ENSECAP00000041304	Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family.	Serum albumin; Serum albumin, the main protein of plasma, has a good binding capacity for water, Ca(2+), Na(+), K(+), fatty acids, hormones, bilirubin and drugs. Its main function is the regulation of the colloidal osmotic pressure of blood. Major zinc transporter in plasma, typically binds about 80% of all plasma zinc (By similarity). Major calcium and magnesium transporter in plasma, binds approximately 45% of circulating calcium and magnesium in plasma (By similarity). Potentially has more than two calcium-binding sites and might additionally bind calcium in a non-specific manner (B [...]	0.913
F2	HPX	ENSECAP00000009701	ENSECAP00000014242	Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family.	Hemopexin; Binds heme and transports it to the liver for breakdown and iron recovery, after which the free hemopexin returns to the circulation.	0.741
F2	SERPINA6	ENSECAP00000009701	ENSECAP00000012843	Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family.	Serpin family A member 6; Belongs to the serpin family.	0.600
F2	SERPINC1	ENSECAP00000009701	ENSECAP00000012335	Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family.	Serpin family C member 1; Belongs to the serpin family.	0.999
FRMD5	LOC100061763	ENSECAP00000050188	ENSECAP00000010124	FERM domain containing 5.	Uncharacterized protein.	0.740
FRMD5	SERPINA6	ENSECAP00000050188	ENSECAP00000012843	FERM domain containing 5.	Serpin family A member 6; Belongs to the serpin family.	0.584
HPX	ALB	ENSECAP00000014242	ENSECAP00000041304	Hemopexin; Binds heme and transports it to the liver for breakdown and iron recovery, after which the free hemopexin returns to the circulation.	Serum albumin; Serum albumin, the main protein of plasma, has a good binding capacity for water, Ca(2+), Na(+), K(+), fatty acids, hormones, bilirubin and drugs. Its main function is the regulation of the colloidal osmotic pressure of blood. Major zinc transporter in plasma, typically binds about 80% of all plasma zinc (By similarity). Major calcium and magnesium transporter in plasma, binds approximately 45% of circulating calcium and magnesium in plasma (By similarity). Potentially has more than two calcium-binding sites and might additionally bind calcium in a non-specific manner (B [...]	0.757
HPX	F2	ENSECAP00000014242	ENSECAP00000009701	Hemopexin; Binds heme and transports it to the liver for breakdown and iron recovery, after which the free hemopexin returns to the circulation.	Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family.	0.741
HPX	SERPINA6	ENSECAP00000014242	ENSECAP00000012843	Hemopexin; Binds heme and transports it to the liver for breakdown and iron recovery, after which the free hemopexin returns to the circulation.	Serpin family A member 6; Belongs to the serpin family.	0.585
HPX	SERPINC1	ENSECAP00000014242	ENSECAP00000012335	Hemopexin; Binds heme and transports it to the liver for breakdown and iron recovery, after which the free hemopexin returns to the circulation.	Serpin family C member 1; Belongs to the serpin family.	0.772
LOC100061639	SERPINA6	ENSECAP00000013705	ENSECAP00000012843	Uncharacterized protein.	Serpin family A member 6; Belongs to the serpin family.	0.651
LOC100061763	FRMD5	ENSECAP00000010124	ENSECAP00000050188	Uncharacterized protein.	FERM domain containing 5.	0.740
LOC100061763	SERPINA6	ENSECAP00000010124	ENSECAP00000012843	Uncharacterized protein.	Serpin family A member 6; Belongs to the serpin family.	0.532
POMC	ALB	ENSECAP00000013923	ENSECAP00000041304	Melanotropin beta; MSH (melanocyte-stimulating hormone) increases the pigmentation of skin by increasing melanin production in melanocytes; Belongs to the POMC family.	Serum albumin; Serum albumin, the main protein of plasma, has a good binding capacity for water, Ca(2+), Na(+), K(+), fatty acids, hormones, bilirubin and drugs. Its main function is the regulation of the colloidal osmotic pressure of blood. Major zinc transporter in plasma, typically binds about 80% of all plasma zinc (By similarity). Major calcium and magnesium transporter in plasma, binds approximately 45% of circulating calcium and magnesium in plasma (By similarity). Potentially has more than two calcium-binding sites and might additionally bind calcium in a non-specific manner (B [...]	0.740
POMC	SERPINA6	ENSECAP00000013923	ENSECAP00000012843	Melanotropin beta; MSH (melanocyte-stimulating hormone) increases the pigmentation of skin by increasing melanin production in melanocytes; Belongs to the POMC family.	Serpin family A member 6; Belongs to the serpin family.	0.555