STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TLL2Metalloendopeptidase. (1020 aa)    
Predicted Functional Partners:
PCOLCE
Procollagen C-endopeptidase enhancer.
   
0.921
MMEL1
Membrane metalloendopeptidase like 1.
   
  
 0.681
MME
Membrane metalloendopeptidase.
      
 0.678
CHRD
Chordin; Dorsalizing factor. Key developmental protein that dorsalizes early vertebrate embryonic tissues by binding to ventralizing TGF-beta family bone morphogenetic proteins (BMPs) and sequestering them in latent complexes.
   
 
 0.656
IDE
Insulin degrading enzyme.
   
  
 0.647
ARHGAP22
Rho GTPase activating protein 22.
      
 0.598
TTC14
Tetratricopeptide repeat domain 14.
      
 0.579
THOP1
Thimet oligopeptidase 1.
      
 0.557
TAL2
TAL bHLH transcription factor 2.
   
  
 0.498
MBTPS2
Membrane bound transcription factor peptidase, site 2.
      
 0.480
Your Current Organism:
Equus caballus
NCBI taxonomy Id: 9796
Other names: E. caballus, Equus przewalskii f. caballus, Equus przewalskii forma caballus, domestic horse, equine, horse
Server load: low (16%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.