STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ITGB1BP2Integrin subunit beta 1 binding protein 2. (348 aa)    
Predicted Functional Partners:
DYM
Dymeclin.
      
 0.706
ABRA
Actin binding Rho activating protein.
   
  
 0.694
SMPX
Small muscle protein X-linked.
   
  
 0.664
ITGB1
Integrin beta; Belongs to the integrin beta chain family.
      
 0.655
LTV1
LTV1 ribosome biogenesis factor.
   
  
 0.649
UNC45B
Unc-45 myosin chaperone B.
   
  
 0.564
MYOZ2
Myozenin 2.
   
  
 0.544
MYPN
Myopalladin.
   
  
 0.532
SUGT1
SGT1 homolog, MIS12 kinetochore complex assembly cochaperone.
   
 
 0.514
HSP90AB1
Heat shock protein HSP 90-beta; Molecular chaperone that promotes the maturation, structural maintenance and proper regulation of specific target proteins involved for instance in cell cycle control and signal transduction. Undergoes a functional cycle that is linked to its ATPase activity. This cycle probably induces conformational changes in the client proteins, thereby causing their activation. Interacts dynamically with various co- chaperones that modulate its substrate recognition, ATPase cycle and chaperone function. Engages with a range of client protein classes via its interact [...]
   
 
 0.509
Your Current Organism:
Equus caballus
NCBI taxonomy Id: 9796
Other names: E. caballus, Equus przewalskii f. caballus, Equus przewalskii forma caballus, domestic horse, equine, horse
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.