STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
WWOXWW domain containing oxidoreductase. (422 aa)    
Predicted Functional Partners:
TFAP2C
Transcription factor AP-2 gamma.
   
 0.942
ERBB4
Receptor protein-tyrosine kinase.
    
 0.896
FHIT
Bis(5'-adenosyl)-triphosphatase.
   
  
 0.837
YWHAE
Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein epsilon; Belongs to the 14-3-3 family.
   
 
 0.812
NKAIN2
Sodium/potassium transporting ATPase interacting 2.
   
  
 0.713
TMEM207
Transmembrane protein 207.
   
  
 0.664
ERBB3
Erb-b2 receptor tyrosine kinase 3.
   
 0.655
GNG10
Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.
   
  
 0.640
FRMD5
FERM domain containing 5.
    
 
 0.636
PDCL3
Phosducin-like protein 3-like protein.
    
 
 0.634
Your Current Organism:
Equus caballus
NCBI taxonomy Id: 9796
Other names: E. caballus, Equus przewalskii f. caballus, Equus przewalskii forma caballus, domestic horse, equine, horse
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