STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TK1Thymidine kinase. (237 aa)    
Predicted Functional Partners:
TYMS
Thymidylate synthetase.
  
 
 0.966
DHFR
DHFR domain-containing protein; Belongs to the dihydrofolate reductase family.
  
 
 0.934
CDA
Cytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis; Belongs to the cytidine and deoxycytidylate deaminase family.
    
 0.899
TYMP
Thymidine phosphorylase; Catalyzes the reversible phosphorolysis of thymidine. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis. Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family.
    
 0.899
TK2
Thymidine kinase 2.
  
 
 0.872
SMUG1
Single-strand-selective monofunctional uracil-DNA glycosylase 1.
    
 0.852
ADAT2
Adenosine deaminase tRNA specific 2.
    
 0.847
DTYMK
Deoxythymidylate kinase.
  
 
 0.839
DCK
Deoxycytidine kinase.
  
 
 0.835
COMTD1
Catechol-O-methyltransferase domain containing 1.
  
 
  0.814
Your Current Organism:
Equus caballus
NCBI taxonomy Id: 9796
Other names: E. caballus, Equus przewalskii f. caballus, Equus przewalskii forma caballus, domestic horse, equine, horse
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