STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ANKZF1Ankyrin repeat and zinc finger domain containing 1. (723 aa)    
Predicted Functional Partners:
CATSPERG
Cation channel sperm associated auxiliary subunit gamma.
      
 0.862
CCDC47
Coiled-coil domain containing 47.
      
 0.788
VCP
Valosin containing protein; Belongs to the AAA ATPase family.
   
 
 0.742
OS9
OS9 endoplasmic reticulum lectin.
   
  
 0.708
SPATA5L1
Spermatogenesis associated 5 like 1.
   
 
 0.690
SPATA5
Spermatogenesis associated 5.
   
 
 0.688
ERLIN2
ER lipid raft associated 2.
   
  
 0.674
SEL1L
SEL1L adaptor subunit of ERAD E3 ubiquitin ligase.
      
 0.671
EIF6
Eukaryotic translation initiation factor 6; Binds to the 60S ribosomal subunit and prevents its association with the 40S ribosomal subunit to form the 80S initiation complex in the cytoplasm. Behaves as a stimulatory translation initiation factor downstream insulin/growth factors. Is also involved in ribosome biogenesis. Associates with pre-60S subunits in the nucleus and is involved in its nuclear export. Cytoplasmic release of TIF6 from 60S subunits and nuclear relocalization is promoted by a RACK1 (RACK1)- dependent protein kinase C activity. In tissues responsive to insulin, contro [...]
    
   0.631
GAS8
Growth arrest specific 8.
      
 0.587
Your Current Organism:
Equus caballus
NCBI taxonomy Id: 9796
Other names: E. caballus, Equus przewalskii f. caballus, Equus przewalskii forma caballus, domestic horse, equine, horse
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.