node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ACADL | CPT1B-2 | ENSECAP00000027277 | ENSECAP00000010542 | Acyl-CoA dehydrogenase long chain. | Carnitine palmitoyltransferase 1B. | 0.727 |
ACADL | PCK1 | ENSECAP00000027277 | ENSECAP00000011966 | Acyl-CoA dehydrogenase long chain. | Phosphoenolpyruvate carboxykinase 1. | 0.461 |
ACADL | PDK4 | ENSECAP00000027277 | ENSECAP00000006579 | Acyl-CoA dehydrogenase long chain. | Protein-serine/threonine kinase. | 0.570 |
ACADL | UCP3 | ENSECAP00000027277 | ENSECAP00000014624 | Acyl-CoA dehydrogenase long chain. | Uncoupling protein 3; Belongs to the mitochondrial carrier (TC 2.A.29) family. | 0.596 |
CPT1B-2 | ACADL | ENSECAP00000010542 | ENSECAP00000027277 | Carnitine palmitoyltransferase 1B. | Acyl-CoA dehydrogenase long chain. | 0.727 |
CPT1B-2 | INS | ENSECAP00000010542 | ENSECAP00000022114 | Carnitine palmitoyltransferase 1B. | Insulin A chain; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. | 0.440 |
CPT1B-2 | NRF1 | ENSECAP00000010542 | ENSECAP00000054389 | Carnitine palmitoyltransferase 1B. | Nuclear respiratory factor 1. | 0.539 |
CPT1B-2 | PDK4 | ENSECAP00000010542 | ENSECAP00000006579 | Carnitine palmitoyltransferase 1B. | Protein-serine/threonine kinase. | 0.758 |
CPT1B-2 | SLC2A4 | ENSECAP00000010542 | ENSECAP00000006413 | Carnitine palmitoyltransferase 1B. | Solute carrier family 2 member 4; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. | 0.600 |
CPT1B-2 | UCP3 | ENSECAP00000010542 | ENSECAP00000014624 | Carnitine palmitoyltransferase 1B. | Uncoupling protein 3; Belongs to the mitochondrial carrier (TC 2.A.29) family. | 0.737 |
INS | CPT1B-2 | ENSECAP00000022114 | ENSECAP00000010542 | Insulin A chain; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. | Carnitine palmitoyltransferase 1B. | 0.440 |
INS | LEP | ENSECAP00000022114 | ENSECAP00000035337 | Insulin A chain; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. | Leptin; Key player in the regulation of energy balance and body weight control. Once released into the circulation, has central and peripheral effects by binding LEPR, found in many tissues, which results in the activation of several major signaling pathways (By similarity). In the hypothalamus, acts as an appetite-regulating factor that induces a decrease in food intake and an increase in energy consumption by inducing anorexinogenic factors and suppressing orexigenic neuropeptides, also regulates bone mass and secretion of hypothalamo-pituitary-adrenal hormones. In the periphery, inc [...] | 0.960 |
INS | MC4R | ENSECAP00000022114 | ENSECAP00000001154 | Insulin A chain; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. | Melanocortin 4 receptor. | 0.721 |
INS | PCK1 | ENSECAP00000022114 | ENSECAP00000011966 | Insulin A chain; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. | Phosphoenolpyruvate carboxykinase 1. | 0.594 |
INS | PDK4 | ENSECAP00000022114 | ENSECAP00000006579 | Insulin A chain; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. | Protein-serine/threonine kinase. | 0.599 |
INS | SIRT1 | ENSECAP00000022114 | ENSECAP00000030286 | Insulin A chain; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. | Sirtuin 1. | 0.794 |
INS | SLC2A4 | ENSECAP00000022114 | ENSECAP00000006413 | Insulin A chain; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. | Solute carrier family 2 member 4; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. | 0.966 |
INS | UCP3 | ENSECAP00000022114 | ENSECAP00000014624 | Insulin A chain; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. | Uncoupling protein 3; Belongs to the mitochondrial carrier (TC 2.A.29) family. | 0.550 |
LEP | INS | ENSECAP00000035337 | ENSECAP00000022114 | Leptin; Key player in the regulation of energy balance and body weight control. Once released into the circulation, has central and peripheral effects by binding LEPR, found in many tissues, which results in the activation of several major signaling pathways (By similarity). In the hypothalamus, acts as an appetite-regulating factor that induces a decrease in food intake and an increase in energy consumption by inducing anorexinogenic factors and suppressing orexigenic neuropeptides, also regulates bone mass and secretion of hypothalamo-pituitary-adrenal hormones. In the periphery, inc [...] | Insulin A chain; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. | 0.960 |
LEP | MC4R | ENSECAP00000035337 | ENSECAP00000001154 | Leptin; Key player in the regulation of energy balance and body weight control. Once released into the circulation, has central and peripheral effects by binding LEPR, found in many tissues, which results in the activation of several major signaling pathways (By similarity). In the hypothalamus, acts as an appetite-regulating factor that induces a decrease in food intake and an increase in energy consumption by inducing anorexinogenic factors and suppressing orexigenic neuropeptides, also regulates bone mass and secretion of hypothalamo-pituitary-adrenal hormones. In the periphery, inc [...] | Melanocortin 4 receptor. | 0.807 |