STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TRERF1Transcriptional regulating factor 1. (1218 aa)    
Predicted Functional Partners:
DNTTIP1
Deoxynucleotidyltransferase terminal interacting protein 1.
    
 
 0.848
ZBTB42
Zinc finger and BTB domain containing 42.
    
 
 0.832
ELMSAN1
ELM2 and Myb/SANT domain containing 1.
    
 
0.648
KCTD19
Potassium channel tetramerization domain containing 19.
   
  
 0.577
RUNX2
Runt-related transcription factor 2; Transcription factor involved in osteoblastic differentiation and skeletal morphogenesis. Essential for the maturation of osteoblasts and both intramembranous and endochondral ossification. CBF binds to the core site, 5'-PYGPYGGT-3', of a number of enhancers and promoters, including murine leukemia virus, polyomavirus enhancer, T-cell receptor enhancers, osteocalcin, osteopontin, bone sialoprotein, alpha 1(I) collagen, LCK, IL-3 and GM-CSF promoters. Inhibits KAT6B-dependent transcriptional activation. In osteoblasts, supports transcription activati [...]
   
  
 0.563
CHST2
Sulfotransferase; Belongs to the sulfotransferase 1 family.
      
 0.562
RBFOX2
RNA binding fox-1 homolog 2.
   
  
 0.544
RAPGEF3
Rap guanine nucleotide exchange factor 3.
      
 0.481
THAP5
THAP domain containing 5.
  
 
   0.478
VAV3
Vav guanine nucleotide exchange factor 3.
   
  
 0.476
Your Current Organism:
Equus caballus
NCBI taxonomy Id: 9796
Other names: E. caballus, Equus przewalskii f. caballus, Equus przewalskii forma caballus, domestic horse, equine, horse
Server load: low (16%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.