STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
BTG2BTG anti-proliferation factor 2. (150 aa)    
Predicted Functional Partners:
CNOT7
CCR4-NOT transcription complex subunit 7.
    
 0.754
CNOT1
CCR4-NOT transcription complex subunit 1.
    
 0.653
HES6
Hes family bHLH transcription factor 6.
      
 0.632
CNOT8
CCR4-NOT transcription complex subunit 8.
    
 0.630
PCBP4
Poly(rC) binding protein 4.
      
 0.621
TMEM245
Transmembrane protein 245.
      
 0.620
JUNB
JunB proto-oncogene, AP-1 transcription factor subunit.
   
  
 0.617
ATF3
Activating transcription factor 3.
   
  
 0.617
CNOT11
CCR4-NOT transcription complex subunit 11.
    
 0.613
EGR1
Early growth response protein; Transcriptional regulator. Recognizes and binds to the DNA sequence 5'-GCG(T/G)GGGCG-3'(EGR-site) in the promoter region of target genes. Binds double-stranded target DNA, irrespective of the cytosine methylation status. Regulates the transcription of numerous target genes, and thereby plays an important role in regulating the response to growth factors, DNA damage, and ischemia. Plays a role in the regulation of cell survival, proliferation and cell death. Belongs to the EGR C2H2-type zinc-finger protein family.
   
  
 0.613
Your Current Organism:
Equus caballus
NCBI taxonomy Id: 9796
Other names: E. caballus, Equus przewalskii f. caballus, Equus przewalskii forma caballus, domestic horse, equine, horse
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.