STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DAPP1Dual adaptor of phosphotyrosine and 3-phosphoinositides 1. (280 aa)    
Predicted Functional Partners:
LYN
Tyrosine-protein kinase.
   
 0.927
RAC1
Rac family small GTPase 1.
   
 0.906
RAC2
Rac family small GTPase 2.
   
 0.905
PLCG2
Phosphoinositide phospholipase C.
     
 0.849
FANCM
FA complementation group M.
   
 0.714
TOX2
TOX high mobility group box family member 2.
   
 
 0.711
USP8
Ubiquitin specific peptidase 8; Belongs to the peptidase C19 family.
     
 0.693
ARHGEF3
Rho guanine nucleotide exchange factor 3.
   
  
 0.680
MTTP
Microsomal triglyceride transfer protein.
   
 
 0.679
PREX2
Phosphatidylinositol-3,4,5-trisphosphate dependent Rac exchange factor 2.
   
 
 0.635
Your Current Organism:
Equus caballus
NCBI taxonomy Id: 9796
Other names: E. caballus, Equus przewalskii f. caballus, Equus przewalskii forma caballus, domestic horse, equine, horse
Server load: low (12%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.