STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LACTB2Lactamase beta 2. (384 aa)    
Predicted Functional Partners:
JSRP1
Junctional sarcoplasmic reticulum protein 1.
    
 
 0.816
PLA2G12B
Phospholipase A2 group XIIB.
   
  
 0.753
MKNK2
MAPK interacting serine/threonine kinase 2; Belongs to the protein kinase superfamily.
   
  
 0.708
SLC16A9
Solute carrier family 16 member 9.
   
  
 0.700
LSS
Terpene cyclase/mutase family member; Belongs to the terpene cyclase/mutase family.
   
 
 0.683
ADI1
1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase; Catalyzes the formation of formate and 2-keto-4- methylthiobutyrate (KMTB) from 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene). Also down-regulates cell migration mediated by MMP14. Belongs to the acireductone dioxygenase (ARD) family.
  
  
 0.677
YBEY
YbeY metalloendoribonuclease.
  
 
 0.639
RPS23
Ribosomal protein S23; Belongs to the universal ribosomal protein uS12 family.
      
 0.576
RAN
GTP-binding nuclear protein Ran; GTP-binding protein involved in nucleocytoplasmic transport. Required for the import of protein into the nucleus and also for RNA export. Involved in chromatin condensation and control of cell cycle. Belongs to the small GTPase superfamily. Ran family.
   
  
 0.571
RING1
Ring finger protein 1.
      
 0.563
Your Current Organism:
Equus caballus
NCBI taxonomy Id: 9796
Other names: E. caballus, Equus przewalskii f. caballus, Equus przewalskii forma caballus, domestic horse, equine, horse
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.