STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
APPL1Adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 1. (708 aa)    
Predicted Functional Partners:
APPL2
Adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 2.
  
 
0.992
DCC
DCC netrin 1 receptor.
   
 0.990
ADIPOR1
Adiponectin receptor 1.
    
 0.988
ADIPOR2
Adiponectin receptor 2.
    
 0.981
CASP3
Caspase-3-like protein; Belongs to the peptidase C14A family.
    
 0.960
NEO1
Neogenin 1.
   
 0.928
CASP9
Caspase 9; Belongs to the peptidase C14A family.
    
 0.921
LOC100147270
Uncharacterized protein.
   
  0.908
IGDCC3
Immunoglobulin superfamily DCC subclass member 3.
   
  0.908
IGDCC4
Immunoglobulin superfamily DCC subclass member 4.
   
  0.908
Your Current Organism:
Equus caballus
NCBI taxonomy Id: 9796
Other names: E. caballus, Equus przewalskii f. caballus, Equus przewalskii forma caballus, domestic horse, equine, horse
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.