STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LRRC43Leucine rich repeat containing 43. (626 aa)    
Predicted Functional Partners:
PPP1CA
Serine/threonine-protein phosphatase; Belongs to the PPP phosphatase family.
   
 0.609
PPP1CC
Serine/threonine-protein phosphatase; Belongs to the PPP phosphatase family.
   
 0.609
ENSECAP00000052394
SER_THR_PHOSPHATASE domain-containing protein.
   
 0.609
ADGRL2
Adhesion G protein-coupled receptor L2; Belongs to the G-protein coupled receptor 2 family.
   
 
 0.580
ADGRL3
Adhesion G protein-coupled receptor L3; Belongs to the G-protein coupled receptor 2 family.
   
 
 0.578
ADGRL1
Adhesion G protein-coupled receptor L1; Belongs to the G-protein coupled receptor 2 family.
    
 
 0.574
PPP1R3C
Protein phosphatase 1 regulatory subunit 3C; Acts as a glycogen-targeting subunit for PP1 and regulates its activity. Activates glycogen synthase, reduces glycogen phosphorylase activity and limits glycogen breakdown.
   
 0.571
PPP1R3D
Protein phosphatase 1 regulatory subunit.
    
 0.566
PPP1R3F
Protein phosphatase 1 regulatory subunit 3F.
    
 0.566
PPP1R3B
Protein phosphatase 1 regulatory subunit.
    
 0.566
Your Current Organism:
Equus caballus
NCBI taxonomy Id: 9796
Other names: E. caballus, Equus przewalskii f. caballus, Equus przewalskii forma caballus, domestic horse, equine, horse
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.