STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PLK1Serine/threonine-protein kinase PLK. (604 aa)    
Predicted Functional Partners:
CDK1
Cyclin dependent kinase 1; Belongs to the protein kinase superfamily.
   
0.998
CCNB1
Cyclin B1; Belongs to the cyclin family.
   
 0.996
PKMYT1
Protein kinase, membrane associated tyrosine/threonine 1; Belongs to the protein kinase superfamily.
   
0.995
CDC20
Cell division cycle 20.
   
 0.994
ESPL1
Extra spindle pole bodies like 1, separase.
   
 0.994
CDC25C
Cell division cycle 25C.
   
 0.993
ERCC6L
ERCC excision repair 6 like, spindle assembly checkpoint helicase.
   
 0.989
CDC20B
Cell division cycle 20B.
   
 0.989
KIF2C
Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.
   
 0.987
BUB1B
BUB1 mitotic checkpoint serine/threonine kinase B.
   
 0.987
Your Current Organism:
Equus caballus
NCBI taxonomy Id: 9796
Other names: E. caballus, Equus przewalskii f. caballus, Equus przewalskii forma caballus, domestic horse, equine, horse
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.