STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CCDC82Coiled-coil domain containing 82. (536 aa)    
Predicted Functional Partners:
GPALPP1
GPALPP motifs containing 1.
   
  
 0.705
LRRC2
Leucine rich repeat containing 2.
      
 0.699
C7H11orf54
Chromosome 7 C11orf54 homolog.
   
  
 0.569
RNF8
E3 ubiquitin-protein ligase RNF8; E3 ubiquitin-protein ligase that plays a key role in DNA damage signaling via 2 distinct roles: by mediating the 'Lys-63'-linked ubiquitination of histones H2A and H2AX and promoting the recruitment of DNA repair proteins at double-strand breaks (DSBs) sites, and by catalyzing 'Lys-48'-linked ubiquitination to remove target proteins from DNA damage sites. Following DNA DSBs, it is recruited to the sites of damage by ATM-phosphorylated MDC1 and catalyzes the 'Lys-63'-linked ubiquitination of histones H2A and H2AX, thereby promoting the formation of TP53 [...]
      
 0.548
KRT34
IF rod domain-containing protein; Belongs to the intermediate filament family.
      
 0.493
FRMD1
FERM domain containing 1.
      
 0.483
NARS1
Asparaginyl-tRNA synthetase.
   
  
 0.482
SLC26A7
Anion exchange transporter.
   
  
 0.475
CACNA2D3
Calcium voltage-gated channel auxiliary subunit alpha2delta 3.
      
 0.472
KCNIP3
Uncharacterized protein.
      
 0.470
Your Current Organism:
Equus caballus
NCBI taxonomy Id: 9796
Other names: E. caballus, Equus przewalskii f. caballus, Equus przewalskii forma caballus, domestic horse, equine, horse
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