STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TWSG1Twisted gastrulation BMP signaling modulator 1. (223 aa)    
Predicted Functional Partners:
CHRD
Chordin; Dorsalizing factor. Key developmental protein that dorsalizes early vertebrate embryonic tissues by binding to ventralizing TGF-beta family bone morphogenetic proteins (BMPs) and sequestering them in latent complexes.
    
 
 0.802
DRC7
Dynein regulatory complex subunit 7.
      
 0.659
CHRDL2
Chordin like 2.
      
 0.653
BMPER
BMP binding endothelial regulator.
   
  
 0.637
SLC9B2
Solute carrier family 9 member B2.
      
 0.636
TXLNG
Taxilin gamma.
      
 0.635
CCDC63
Coiled-coil domain containing 63.
      
 0.622
ASXL2
ASXL transcriptional regulator 2.
      
 0.606
CRIM1
Cysteine rich transmembrane BMP regulator 1.
      
 0.577
MMP21
Matrix metallopeptidase 21.
      
 0.539
Your Current Organism:
Equus caballus
NCBI taxonomy Id: 9796
Other names: E. caballus, Equus przewalskii f. caballus, Equus przewalskii forma caballus, domestic horse, equine, horse
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.