STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
IRF3Interferon regulatory factor 3. (426 aa)    
Predicted Functional Partners:
TBK1
TANK binding kinase 1.
   
 0.999
CREBBP
CREB binding protein.
    
 0.999
IFNB1
Interferon beta; Has antiviral, antibacterial and anticancer activities.
     
 0.997
EP300
E1A binding protein p300.
    
 0.992
ISG15
ISG15 ubiquitin like modifier.
   
 0.990
MAVS
Mitochondrial antiviral signaling protein.
    
 0.990
IKBKE
Inhibitor of nuclear factor kappa B kinase subunit epsilon.
   
 0.987
TICAM1
Toll like receptor adaptor molecule 1.
    
 0.984
LOC100147174
Uncharacterized protein.
     
 0.980
PIN1
Peptidyl-prolyl cis-trans isomerase.
   
 0.978
Your Current Organism:
Equus caballus
NCBI taxonomy Id: 9796
Other names: E. caballus, Equus przewalskii f. caballus, Equus przewalskii forma caballus, domestic horse, equine, horse
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.