TYRO3 protein (Equus caballus) - STRING interaction network

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Score

TYRO3

TYRO3 protein tyrosine kinase. (1036 aa)

Predicted Functional Partners:

GAS6

0.995

PROS1

0.908

ICAM3

0.682

ADAM15

0.573

PTPRF

0.572

TAB1

0.559

TRAF6

0.558

MIB2

0.543

TNF

0.527

THBS1

0.526

Your Current Organism:

Equus caballus

NCBI taxonomy Id: 9796
Other names: E. caballus, Equus przewalskii f. caballus, Equus przewalskii forma caballus, domestic horse, equine, horse

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ADAM15	PTPRF	ENSECAP00000033798	ENSECAP00000037312	ADAM metallopeptidase domain 15.	Protein tyrosine phosphatase receptor type F.	0.693
ADAM15	TYRO3	ENSECAP00000033798	ENSECAP00000015977	ADAM metallopeptidase domain 15.	TYRO3 protein tyrosine kinase.	0.573
GAS6	THBS1	ENSECAP00000000011	ENSECAP00000007423	Growth arrest specific 6.	Thrombospondin 1.	0.475
GAS6	TYRO3	ENSECAP00000000011	ENSECAP00000015977	Growth arrest specific 6.	TYRO3 protein tyrosine kinase.	0.995
ICAM3	TYRO3	ENSECAP00000022282	ENSECAP00000015977	Intercellular adhesion molecule 3.	TYRO3 protein tyrosine kinase.	0.682
MIB2	TNF	ENSECAP00000012797	ENSECAP00000001460	Mindbomb E3 ubiquitin protein ligase 2.	Tumor necrosis factor, membrane form; Cytokine that binds to TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. It is mainly secreted by macrophages and can induce cell death of certain tumor cell lines. It is potent pyrogen causing fever by direct action or by stimulation of interleukin-1 secretion and is implicated in the induction of cachexia, Under certain conditions it can stimulate cell proliferation and induce cell differentiation (By similarity). Induces insulin resistance in adipocytes via inhibition of insulin-induced IRS1 tyrosine phosphorylation and insulin-induced glucose uptake. Induces [...]	0.702
MIB2	TRAF6	ENSECAP00000012797	ENSECAP00000018618	Mindbomb E3 ubiquitin protein ligase 2.	TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.	0.612
MIB2	TYRO3	ENSECAP00000012797	ENSECAP00000015977	Mindbomb E3 ubiquitin protein ligase 2.	TYRO3 protein tyrosine kinase.	0.543
PROS1	TYRO3	ENSECAP00000030358	ENSECAP00000015977	Protein S.	TYRO3 protein tyrosine kinase.	0.908
PTPRF	ADAM15	ENSECAP00000037312	ENSECAP00000033798	Protein tyrosine phosphatase receptor type F.	ADAM metallopeptidase domain 15.	0.693
PTPRF	TYRO3	ENSECAP00000037312	ENSECAP00000015977	Protein tyrosine phosphatase receptor type F.	TYRO3 protein tyrosine kinase.	0.572
TAB1	TNF	ENSECAP00000028874	ENSECAP00000001460	TGF-beta activated kinase 1 (MAP3K7) binding protein 1.	Tumor necrosis factor, membrane form; Cytokine that binds to TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. It is mainly secreted by macrophages and can induce cell death of certain tumor cell lines. It is potent pyrogen causing fever by direct action or by stimulation of interleukin-1 secretion and is implicated in the induction of cachexia, Under certain conditions it can stimulate cell proliferation and induce cell differentiation (By similarity). Induces insulin resistance in adipocytes via inhibition of insulin-induced IRS1 tyrosine phosphorylation and insulin-induced glucose uptake. Induces [...]	0.972
TAB1	TRAF6	ENSECAP00000028874	ENSECAP00000018618	TGF-beta activated kinase 1 (MAP3K7) binding protein 1.	TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.	0.999
TAB1	TYRO3	ENSECAP00000028874	ENSECAP00000015977	TGF-beta activated kinase 1 (MAP3K7) binding protein 1.	TYRO3 protein tyrosine kinase.	0.559
THBS1	GAS6	ENSECAP00000007423	ENSECAP00000000011	Thrombospondin 1.	Growth arrest specific 6.	0.475
THBS1	TNF	ENSECAP00000007423	ENSECAP00000001460	Thrombospondin 1.	Tumor necrosis factor, membrane form; Cytokine that binds to TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. It is mainly secreted by macrophages and can induce cell death of certain tumor cell lines. It is potent pyrogen causing fever by direct action or by stimulation of interleukin-1 secretion and is implicated in the induction of cachexia, Under certain conditions it can stimulate cell proliferation and induce cell differentiation (By similarity). Induces insulin resistance in adipocytes via inhibition of insulin-induced IRS1 tyrosine phosphorylation and insulin-induced glucose uptake. Induces [...]	0.479
THBS1	TYRO3	ENSECAP00000007423	ENSECAP00000015977	Thrombospondin 1.	TYRO3 protein tyrosine kinase.	0.526
TNF	MIB2	ENSECAP00000001460	ENSECAP00000012797	Tumor necrosis factor, membrane form; Cytokine that binds to TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. It is mainly secreted by macrophages and can induce cell death of certain tumor cell lines. It is potent pyrogen causing fever by direct action or by stimulation of interleukin-1 secretion and is implicated in the induction of cachexia, Under certain conditions it can stimulate cell proliferation and induce cell differentiation (By similarity). Induces insulin resistance in adipocytes via inhibition of insulin-induced IRS1 tyrosine phosphorylation and insulin-induced glucose uptake. Induces [...]	Mindbomb E3 ubiquitin protein ligase 2.	0.702
TNF	TAB1	ENSECAP00000001460	ENSECAP00000028874	Tumor necrosis factor, membrane form; Cytokine that binds to TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. It is mainly secreted by macrophages and can induce cell death of certain tumor cell lines. It is potent pyrogen causing fever by direct action or by stimulation of interleukin-1 secretion and is implicated in the induction of cachexia, Under certain conditions it can stimulate cell proliferation and induce cell differentiation (By similarity). Induces insulin resistance in adipocytes via inhibition of insulin-induced IRS1 tyrosine phosphorylation and insulin-induced glucose uptake. Induces [...]	TGF-beta activated kinase 1 (MAP3K7) binding protein 1.	0.972
TNF	THBS1	ENSECAP00000001460	ENSECAP00000007423	Tumor necrosis factor, membrane form; Cytokine that binds to TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. It is mainly secreted by macrophages and can induce cell death of certain tumor cell lines. It is potent pyrogen causing fever by direct action or by stimulation of interleukin-1 secretion and is implicated in the induction of cachexia, Under certain conditions it can stimulate cell proliferation and induce cell differentiation (By similarity). Induces insulin resistance in adipocytes via inhibition of insulin-induced IRS1 tyrosine phosphorylation and insulin-induced glucose uptake. Induces [...]	Thrombospondin 1.	0.479