STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
GRNAntimicrobial peptide eNAP-1; Has antimicrobial activity against Gram-negative and Gram- positive bacteria; Belongs to the granulin family. (587 aa)    
Predicted Functional Partners:
SORT1
Sortilin.
   
 
 0.834
CTSD
Peptidase A1 domain-containing protein; Belongs to the peptidase A1 family.
   
 0.758
TARDBP
TAR DNA-binding protein 43-like protein.
    
 
 0.741
MAPT
Microtubule-associated protein.
      
 0.740
CHMP2B
Charged multivesicular body protein 2B.
      
 0.740
CTSZ
Cathepsin Z; Belongs to the peptidase C1 family.
   
 0.723
PSAP
Prosaposin; Prosaposin: Behaves as a myelinotrophic and neurotrophic factor, these effects are mediated by its G-protein-coupled receptors, GPR37 and GPR37L1, undergoing ligand-mediated internalization followed by ERK phosphorylation signaling.
   
 0.715
TREML1
Triggering receptor expressed on myeloid cells like 1.
   
  
 0.692
LAMP1
Lysosomal associated membrane protein 1.
   
 
 0.681
TMEM106B
Transmembrane protein 106B.
      
 0.664
Your Current Organism:
Equus caballus
NCBI taxonomy Id: 9796
Other names: E. caballus, Equus przewalskii f. caballus, Equus przewalskii forma caballus, domestic horse, equine, horse
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